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| 15.02.1981 | Racing Santander | - | Rayo Vallecano | 2:1 | ||
| CD Castellón | - | CE Sabadell | 2:1 | |||
| Cádiz CF | - | CF Palencia | 3:1 | |||
| Deportivo Alavés | - | Barakaldo CF | 2:0 | |||
| Levante UD | - | Club Getafe Deportivo | 2:2 | |||
| Atlético Madrileño | - | AgD Ceuta | 3:0 | |||
| Recreativo Huelva | - | Burgos CF | 1:1 | |||
| Real Oviedo | - | Castilla CF | 1:0 | |||
| CD Málaga | - | Granada CF | 2:0 | |||
| Linares CF | - | Elche CF | 1:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing Santander | 24 | 11 | 7 | 6 | 32:23 | 9 | 29:19 |
| 2 |
|
CD Castellón | 24 | 9 | 11 | 4 | 30:22 | 8 | 29:19 |
| 3 |
|
Deportivo Alavés | 24 | 11 | 6 | 7 | 34:20 | 14 | 28:20 |
| 4 |
|
Rayo Vallecano | 24 | 10 | 8 | 6 | 24:15 | 9 | 28:20 |
| 5 |
|
Atlético Madrileño | 24 | 11 | 6 | 7 | 33:31 | 2 | 28:20 |
| 6 |
|
CD Málaga | 24 | 9 | 10 | 5 | 27:27 | 0 | 28:20 |
| 7 |
|
Elche CF | 24 | 9 | 8 | 7 | 35:28 | 7 | 26:22 |
| 8 |
|
Levante UD | 24 | 10 | 6 | 8 | 23:18 | 5 | 26:22 |
| 9 |
|
Cádiz CF | 24 | 11 | 4 | 9 | 33:29 | 4 | 26:22 |
| 10 |
|
Recreativo Huelva | 24 | 8 | 9 | 7 | 21:21 | 0 | 25:23 |
| 11 |
|
Real Oviedo | 24 | 8 | 8 | 8 | 26:25 | 1 | 24:24 |
| 12 |
|
CE Sabadell | 24 | 8 | 7 | 9 | 28:30 | -2 | 23:25 |
| 13 |
|
Barakaldo CF | 24 | 8 | 7 | 9 | 24:29 | -5 | 23:25 |
| 14 |
|
Castilla CF | 24 | 8 | 6 | 10 | 29:28 | 1 | 22:26 |
| 15 |
|
Burgos CF | 24 | 8 | 6 | 10 | 30:30 | 0 | 22:26 |
| 16 |
|
Granada CF | 24 | 6 | 9 | 9 | 22:28 | -6 | 21:27 |
| 17 |
|
CF Palencia | 24 | 7 | 6 | 11 | 16:23 | -7 | 20:28 |
| 18 |
|
Club Getafe Deportivo | 24 | 5 | 8 | 11 | 26:40 | -14 | 18:30 |
| 19 |
|
AgD Ceuta | 24 | 6 | 5 | 13 | 23:35 | -12 | 17:31 |
| 20 |
|
Linares CF | 24 | 5 | 7 | 12 | 17:31 | -14 | 17:31 |
