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| 19.02.2022 | 15:00 | FC Sochaux | - | AC Ajaccio | 0:1 (0:0) | |
| 19:00 | AS Nancy Lorraine | - | USL Dunkerque | 2:0 (1:0) | ||
| 19:00 | EA Guingamp | - | Paris FC | 1:1 (0:0) | ||
| 19:00 | Chamois Niortais | - | AJ Auxerre | 0:1 (0:1) | ||
| 19:00 | Pau FC | - | SM Caen | 1:0 (0:0) | ||
| 19:00 | Nîmes Olympique | - | Grenoble Foot 38 | 3:1 (1:0) | ||
| 19:00 | Rodez AF | - | Amiens SC | 1:1 (1:1) | ||
| 19:00 | SC Bastia | - | Dijon FCO | 0:0 (0:0) | ||
| 19:00 | US Quevilly-Rouen | - | Valenciennes FC | 1:1 (1:1) | ||
| 21.02.2022 | 20:45 | Toulouse FC | - | Havre AC | 4:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 25 | 14 | 9 | 2 | 56:21 | 35 | 51 |
| 2 |
|
Paris FC | 25 | 14 | 6 | 5 | 36:21 | 15 | 48 |
| 3 |
|
AC Ajaccio | 25 | 13 | 6 | 6 | 22:13 | 9 | 45 |
| 4 |
|
FC Sochaux | 25 | 12 | 8 | 5 | 28:21 | 7 | 44 |
| 5 |
|
AJ Auxerre | 25 | 11 | 9 | 5 | 37:27 | 10 | 42 |
| 6 |
|
Chamois Niortais | 25 | 10 | 5 | 10 | 28:26 | 2 | 35 |
| 7 |
|
Nîmes Olympique | 25 | 10 | 5 | 10 | 32:32 | 0 | 35 |
| 8 |
|
Havre AC | 25 | 8 | 11 | 6 | 24:24 | 0 | 35 |
| 9 |
|
Pau FC | 25 | 10 | 5 | 10 | 27:28 | -1 | 35 |
| 10 |
|
EA Guingamp | 25 | 7 | 10 | 8 | 27:33 | -6 | 31 |
| 11 |
|
Amiens SC | 25 | 6 | 12 | 7 | 31:24 | 7 | 30 |
| 12 |
|
Dijon FCO | 25 | 9 | 3 | 13 | 29:34 | -5 | 30 |
| 13 |
|
Rodez AF | 25 | 7 | 9 | 9 | 21:26 | -5 | 30 |
| 14 |
|
SM Caen | 25 | 7 | 8 | 10 | 31:28 | 3 | 29 |
| 15 |
|
SC Bastia | 25 | 6 | 11 | 8 | 25:24 | 1 | 29 |
| 16 |
|
US Quevilly-Rouen | 25 | 7 | 8 | 10 | 23:34 | -11 | 29 |
| 17 |
|
Valenciennes FC | 25 | 6 | 9 | 10 | 25:35 | -10 | 27 |
| 18 |
|
Grenoble Foot 38 | 25 | 7 | 4 | 14 | 20:34 | -14 | 25 |
| 19 |
|
USL Dunkerque | 25 | 6 | 6 | 13 | 19:31 | -12 | 24 |
| 20 |
|
AS Nancy Lorraine | 25 | 4 | 8 | 13 | 21:46 | -25 | 20 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
