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| 18.01.2019 | 20:00 | Sparta Rotterdam | - | Roda JC Kerkrade | 2:2 (2:1) | |
| 20:00 | FC Volendam | - | FC Eindhoven | 1:3 (1:0) | ||
| 20:00 | RKC Waalwijk | - | Jong Ajax | 4:1 (4:0) | ||
| 20:00 | Go Ahead Eagles | - | Almere City FC | 2:1 (1:1) | ||
| 20:00 | FC Den Bosch | - | TOP Oss | 3:0 (0:0) | ||
| 20:00 | NEC Nijmegen | - | Telstar | 1:1 (1:1) | ||
| 20:00 | Helmond Sport | - | SC Cambuur | 0:1 (0:0) | ||
| 20:00 | Jong AZ Alkmaar | - | FC Dordrecht | 0:1 (0:0) | ||
| 20:00 | FC Twente | - | Jong FC Utrecht | 1:0 (1:0) | ||
| 21.01.2019 | 20:00 | Jong PSV | - | MVV Maastricht | 2:2 (1:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Den Bosch | 21 | 14 | 4 | 3 | 42:21 | 21 | 46 |
| 2 |
|
FC Twente | 21 | 14 | 2 | 5 | 39:22 | 17 | 44 |
| 3 |
|
Go Ahead Eagles | 21 | 13 | 3 | 5 | 37:23 | 14 | 42 |
| 4 |
|
Sparta Rotterdam | 21 | 11 | 7 | 3 | 43:23 | 20 | 40 |
| 5 |
|
Roda JC Kerkrade | 21 | 10 | 5 | 6 | 35:27 | 8 | 35 |
| 6 |
|
Jong PSV | 21 | 9 | 7 | 5 | 48:38 | 10 | 34 |
| 7 |
|
TOP Oss | 21 | 10 | 4 | 7 | 27:22 | 5 | 34 |
| 8 |
|
Jong Ajax | 21 | 10 | 2 | 9 | 40:33 | 7 | 32 |
| 9 |
|
SC Cambuur | 21 | 9 | 5 | 7 | 29:28 | 1 | 32 |
| 10 |
|
RKC Waalwijk | 21 | 9 | 2 | 10 | 31:32 | -1 | 29 |
| 11 |
|
FC Eindhoven | 21 | 8 | 4 | 9 | 27:27 | 0 | 28 |
| 12 |
|
Almere City FC | 21 | 8 | 4 | 9 | 32:37 | -5 | 28 |
| 13 |
|
FC Volendam | 21 | 7 | 6 | 8 | 26:31 | -5 | 27 |
| 14 |
|
MVV Maastricht | 21 | 7 | 6 | 8 | 22:28 | -6 | 27 |
| 15 |
|
NEC Nijmegen | 21 | 7 | 5 | 9 | 34:37 | -3 | 26 |
| 16 |
|
Telstar | 21 | 7 | 3 | 11 | 24:35 | -11 | 24 |
| 17 |
|
Helmond Sport | 21 | 2 | 8 | 11 | 21:33 | -12 | 14 |
| 18 |
|
FC Dordrecht | 21 | 3 | 5 | 13 | 23:43 | -20 | 14 |
| 19 |
|
Jong FC Utrecht | 21 | 3 | 5 | 13 | 24:46 | -22 | 14 |
| 20 |
|
Jong AZ Alkmaar | 21 | 2 | 7 | 12 | 25:43 | -18 | 13 |
| Promotie | |
| Play-offs | |
| Play-offs |
