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| 08.02.2019 | 20:00 | SC Cambuur | - | NEC Nijmegen | 1:1 (1:0) | |
| 20:00 | Sparta Rotterdam | - | FC Twente | 0:3 (0:2) | ||
| 20:00 | FC Den Bosch | - | FC Volendam | 1:1 (0:1) | ||
| 20:00 | TOP Oss | - | MVV Maastricht | 1:3 (0:1) | ||
| 20:00 | Almere City FC | - | Jong AZ Alkmaar | 2:0 (1:0) | ||
| 20:00 | Telstar | - | RKC Waalwijk | 0:3 (0:0) | ||
| 20:00 | FC Eindhoven | - | Jong PSV | 1:2 (0:0) | ||
| 20:00 | Helmond Sport | - | FC Dordrecht | 1:2 (1:0) | ||
| 11.02.2019 | 20:00 | Jong FC Utrecht | - | Go Ahead Eagles | 2:4 (0:2) | |
| 20:00 | Jong Ajax | - | Roda JC Kerkrade | 5:1 (4:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Twente | 24 | 17 | 2 | 5 | 49:24 | 25 | 53 |
| 2 |
|
FC Den Bosch | 24 | 14 | 5 | 5 | 44:26 | 18 | 47 |
| 3 |
|
Go Ahead Eagles | 24 | 14 | 4 | 6 | 42:27 | 15 | 46 |
| 4 |
|
Jong PSV | 24 | 12 | 7 | 5 | 56:41 | 15 | 43 |
| 5 |
|
Sparta Rotterdam | 24 | 11 | 9 | 4 | 46:29 | 17 | 42 |
| 6 |
|
Roda JC Kerkrade | 24 | 11 | 5 | 8 | 43:36 | 7 | 38 |
| 7 |
|
RKC Waalwijk | 24 | 12 | 2 | 10 | 38:34 | 4 | 38 |
| 8 |
|
Jong Ajax | 24 | 11 | 3 | 10 | 49:40 | 9 | 36 |
| 9 |
|
MVV Maastricht | 24 | 10 | 6 | 8 | 30:29 | 1 | 36 |
| 10 |
|
TOP Oss | 24 | 10 | 5 | 9 | 30:29 | 1 | 35 |
| 11 |
|
FC Eindhoven | 24 | 10 | 4 | 10 | 31:29 | 2 | 34 |
| 12 |
|
SC Cambuur | 24 | 9 | 7 | 8 | 32:32 | 0 | 34 |
| 13 |
|
Almere City FC | 24 | 10 | 4 | 10 | 37:41 | -4 | 34 |
| 14 |
|
FC Volendam | 24 | 8 | 8 | 8 | 32:35 | -3 | 32 |
| 15 |
|
NEC Nijmegen | 24 | 8 | 7 | 9 | 40:40 | 0 | 31 |
| 16 |
|
Telstar | 24 | 7 | 4 | 13 | 25:41 | -16 | 25 |
| 17 |
|
FC Dordrecht | 24 | 4 | 6 | 14 | 29:50 | -21 | 18 |
| 18 |
|
Jong AZ Alkmaar | 24 | 3 | 7 | 14 | 29:52 | -23 | 16 |
| 19 |
|
Helmond Sport | 24 | 2 | 8 | 14 | 23:42 | -19 | 14 |
| 20 |
|
Jong FC Utrecht | 24 | 3 | 5 | 16 | 28:56 | -28 | 14 |
| Promotie | |
| Play-offs | |
| Play-offs |
