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| 03.04.2010 | 18:45 | VVV-Venlo | - | FC Twente | 0:2 (0:1) | |
| 19:45 | Vitesse | - | FC Groningen | 3:0 (0:0) | ||
| 19:45 | AZ Alkmaar | - | FC Utrecht | 2:0 (1:0) | ||
| 19:45 | Roda JC Kerkrade | - | RKC Waalwijk | 5:1 (2:1) | ||
| 20:45 | sc Heerenveen | - | Sparta Rotterdam | 4:1 (3:0) | ||
| 04.04.2010 | 12:30 | Feyenoord | - | NAC Breda | 0:0 (0:0) | |
| 12:30 | ADO Den Haag | - | AFC Ajax | 0:1 (0:0) | ||
| 14:30 | Heracles Almelo | - | NEC Nijmegen | 2:0 (0:0) | ||
| 14:30 | Willem II | - | PSV | 0:1 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Twente | 30 | 24 | 5 | 1 | 57:22 | 35 | 77 |
| 2 |
|
AFC Ajax | 30 | 23 | 4 | 3 | 89:19 | 70 | 73 |
| 3 |
|
PSV | 30 | 22 | 6 | 2 | 66:25 | 41 | 72 |
| 4 |
|
Feyenoord | 30 | 15 | 11 | 4 | 45:27 | 18 | 56 |
| 5 |
|
AZ Alkmaar | 30 | 17 | 3 | 10 | 59:33 | 26 | 54 |
| 6 |
|
Heracles Almelo | 30 | 15 | 4 | 11 | 45:41 | 4 | 49 |
| 7 |
|
FC Utrecht | 30 | 13 | 9 | 8 | 33:28 | 5 | 48 |
| 8 |
|
FC Groningen | 30 | 12 | 6 | 12 | 39:42 | -3 | 42 |
| 9 |
|
NAC Breda | 30 | 11 | 8 | 11 | 40:46 | -6 | 41 |
| 10 |
|
Roda JC Kerkrade | 30 | 11 | 5 | 14 | 44:53 | -9 | 38 |
| 11 |
|
sc Heerenveen | 30 | 11 | 2 | 17 | 40:54 | -14 | 35 |
| 12 |
|
Vitesse | 30 | 8 | 6 | 16 | 32:50 | -18 | 30 |
| 13 |
|
VVV-Venlo | 30 | 6 | 11 | 13 | 37:45 | -8 | 29 |
| 14 |
|
NEC Nijmegen | 30 | 7 | 8 | 15 | 31:51 | -20 | 29 |
| 15 |
|
Sparta Rotterdam | 30 | 6 | 7 | 17 | 28:56 | -28 | 25 |
| 16 |
|
ADO Den Haag | 30 | 5 | 9 | 16 | 28:52 | -24 | 24 |
| 17 |
|
Willem II | 30 | 7 | 2 | 21 | 34:58 | -24 | 23 |
| 18 |
|
RKC Waalwijk | 30 | 4 | 0 | 26 | 24:69 | -45 | 12 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
