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| 12.11.2010 | 16:00 | FK Saturn | - | FK Amkar Perm | 2:2 (0:0) | |
| 13.11.2010 | 12:30 | FK Tom Tomsk | - | Spartak Vladikavkaz | 1:1 (1:0) | |
| 14:45 | Terek Grozny | - | Anzhi Makhachkala | 1:3 (1:1) | ||
| 17:00 | Dinamo Moskou | - | Rubin Kazan | 2:2 (2:0) | ||
| 14.11.2010 | 12:00 | Spartak Nalchik | - | CSKA Moskou | 1:1 (0:0) | |
| 13:00 | Zenit St. Petersburg | - | FK Rostov | 5:0 (1:0) | ||
| 14:15 | Lokomotiv Moskou | - | Sibir Novosibirsk | 1:1 (0:0) | ||
| 17:00 | Spartak Moskou | - | Krylia Sovetov | 0:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 28 | 20 | 6 | 2 | 59:19 | 40 | 66 |
| 2 |
|
CSKA Moskou | 28 | 17 | 7 | 4 | 48:21 | 27 | 58 |
| 3 |
|
Rubin Kazan | 28 | 15 | 11 | 2 | 35:14 | 21 | 56 |
| 4 |
|
Spartak Moskou | 28 | 13 | 9 | 6 | 41:29 | 12 | 48 |
| 5 |
|
Spartak Nalchik | 28 | 12 | 8 | 8 | 38:31 | 7 | 44 |
| 6 |
|
Lokomotiv Moskou | 28 | 12 | 8 | 8 | 32:28 | 4 | 44 |
| 7 |
|
Dinamo Moskou | 28 | 9 | 12 | 7 | 37:29 | 8 | 39 |
| 8 |
|
FK Rostov | 28 | 10 | 4 | 14 | 25:39 | -14 | 34 |
| 9 |
|
Terek Grozny | 28 | 8 | 8 | 12 | 26:31 | -5 | 32 |
| 10 |
|
FK Tom Tomsk | 28 | 8 | 7 | 13 | 31:42 | -11 | 31 |
| 11 |
|
Anzhi Makhachkala | 28 | 8 | 6 | 14 | 25:36 | -11 | 30 |
| 12 |
|
FK Saturn | 28 | 7 | 9 | 12 | 24:36 | -12 | 30 |
| 13 |
|
Krylia Sovetov | 28 | 6 | 9 | 13 | 27:40 | -13 | 27 |
| 14 |
|
FK Amkar Perm | 28 | 7 | 5 | 16 | 21:34 | -13 | 26 |
| 15 |
|
Spartak Vladikavkaz | 28 | 6 | 8 | 14 | 22:39 | -17 | 26 |
| 16 |
|
Sibir Novosibirsk | 28 | 4 | 7 | 17 | 33:56 | -23 | 19 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
