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| 05.12.2020 | 12:00 | Lokomotiv Moskou | - | Rubin Kazan | 3:1 (1:1) | |
| 14:30 | Spartak Moskou | - | FK Tambov | 5:1 (1:0) | ||
| 17:00 | FK Krasnodar | - | Rotor Volgograd | 5:0 (3:0) | ||
| 17:00 | Zenit St. Petersburg | - | FK Ural | 5:1 (4:0) | ||
| 06.12.2020 | 12:00 | FK Rostov | - | FK Ufa | 0:1 (0:0) | |
| 14:30 | Dinamo Moskou | - | Arsenal Tula | 1:0 (1:0) | ||
| 17:00 | CSKA Moskou | - | FK Khimki | 2:2 (1:0) | ||
| 07.12.2020 | 17:00 | FK Sochi | - | Akhmat Grozny | 2:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zenit St. Petersburg | 17 | 10 | 5 | 2 | 37:13 | 24 | 35 |
| 2 |
|
Spartak Moskou | 17 | 10 | 5 | 2 | 32:17 | 15 | 35 |
| 3 |
|
CSKA Moskou | 17 | 10 | 3 | 4 | 30:14 | 16 | 33 |
| 4 |
|
Dinamo Moskou | 17 | 9 | 3 | 5 | 23:16 | 7 | 30 |
| 5 |
|
FK Rostov | 17 | 9 | 2 | 6 | 22:17 | 5 | 29 |
| 6 |
|
Lokomotiv Moskou | 17 | 8 | 4 | 5 | 19:17 | 2 | 28 |
| 7 |
|
FK Sochi | 17 | 7 | 6 | 4 | 25:22 | 3 | 27 |
| 8 |
|
Akhmat Grozny | 17 | 7 | 4 | 6 | 19:20 | -1 | 25 |
| 9 |
|
FK Krasnodar | 17 | 7 | 3 | 7 | 29:19 | 10 | 24 |
| 10 |
|
Rubin Kazan | 17 | 7 | 3 | 7 | 23:25 | -2 | 24 |
| 11 |
|
FK Ural | 17 | 4 | 7 | 6 | 13:20 | -7 | 19 |
| 12 |
|
FK Khimki | 17 | 5 | 4 | 8 | 20:28 | -8 | 19 |
| 13 |
|
Arsenal Tula | 17 | 3 | 5 | 9 | 17:28 | -11 | 14 |
| 14 |
|
FK Ufa | 17 | 3 | 4 | 10 | 14:29 | -15 | 13 |
| 15 |
|
FK Tambov | 17 | 3 | 3 | 11 | 12:27 | -15 | 12 |
| 16 |
|
Rotor Volgograd | 17 | 1 | 5 | 11 | 7:30 | -23 | 8 |
| Champions League | |
| Champions League Kwali. | |
| Europa League Kwali. | |
| Promotie en degradatie | |
| Degradatie |
