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| 05.05.2010 | 18:00 | FK Dukla Banská Bystrica | - | FC Nitra | 3:1 (1:1) | |
| 18:00 | MFK Petržalka | - | MFK Košice | 0:0 (0:0) | ||
| 18:00 | MFK Ružomberok | - | FK Senica | 2:1 (0:1) | ||
| 18:00 | FC DAC 1904 | - | Slovan Bratislava | 0:1 (0:1) | ||
| 18:00 | MFK Dubnica | - | MŠK Žilina | 1:1 (0:1) | ||
| 18:00 | 1. FC Tatran Prešov | - | Spartak Trnava | 3:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
MŠK Žilina | 31 | 22 | 3 | 6 | 54:16 | 38 | 69 |
| 2 |
|
Slovan Bratislava | 31 | 19 | 7 | 5 | 47:22 | 25 | 64 |
| 3 |
|
FK Dukla Banská Bystrica | 31 | 15 | 10 | 6 | 44:27 | 17 | 55 |
| 4 |
|
FC Nitra | 31 | 13 | 6 | 12 | 38:34 | 4 | 45 |
| 5 |
|
MFK Ružomberok | 31 | 12 | 7 | 12 | 32:35 | -3 | 43 |
| 6 |
|
Spartak Trnava | 31 | 12 | 5 | 14 | 51:43 | 8 | 41 |
| 7 |
|
FK Senica | 31 | 11 | 7 | 13 | 31:41 | -10 | 40 |
| 8 |
|
1. FC Tatran Prešov | 31 | 11 | 4 | 16 | 31:35 | -4 | 37 |
| 9 |
|
MFK Dubnica | 31 | 7 | 11 | 13 | 25:41 | -16 | 32 |
| 10 |
|
FC DAC 1904 | 31 | 6 | 12 | 13 | 26:42 | -16 | 30 |
| 11 |
|
MFK Petržalka | 31 | 7 | 8 | 16 | 32:48 | -16 | 29 |
| 12 |
|
MFK Košice | 31 | 7 | 8 | 16 | 28:55 | -27 | 29 |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
