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| 08.05.2010 | 18:00 | FK Senica | - | FC Nitra | 1:2 (0:0) | |
| 18:00 | MFK Ružomberok | - | MFK Petržalka | 1:0 (0:0) | ||
| 18:00 | Slovan Bratislava | - | FK Dukla Banská Bystrica | 2:0 (1:0) | ||
| 18:00 | MFK Košice | - | 1. FC Tatran Prešov | 3:1 (1:0) | ||
| 18:00 | Spartak Trnava | - | MFK Dubnica | 0:1 (0:0) | ||
| 18:00 | MŠK Žilina | - | FC DAC 1904 | 4:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
MŠK Žilina | 32 | 23 | 3 | 6 | 58:16 | 42 | 72 |
| 2 |
|
Slovan Bratislava | 32 | 20 | 7 | 5 | 49:22 | 27 | 67 |
| 3 |
|
FK Dukla Banská Bystrica | 32 | 15 | 10 | 7 | 44:29 | 15 | 55 |
| 4 |
|
FC Nitra | 32 | 14 | 6 | 12 | 40:35 | 5 | 48 |
| 5 |
|
MFK Ružomberok | 32 | 13 | 7 | 12 | 33:35 | -2 | 46 |
| 6 |
|
Spartak Trnava | 32 | 12 | 5 | 15 | 51:44 | 7 | 41 |
| 7 |
|
FK Senica | 32 | 11 | 7 | 14 | 32:43 | -11 | 40 |
| 8 |
|
1. FC Tatran Prešov | 32 | 11 | 4 | 17 | 32:38 | -6 | 37 |
| 9 |
|
MFK Dubnica | 32 | 8 | 11 | 13 | 26:41 | -15 | 35 |
| 10 |
|
MFK Košice | 32 | 8 | 8 | 16 | 31:56 | -25 | 32 |
| 11 |
|
FC DAC 1904 | 32 | 6 | 12 | 14 | 26:46 | -20 | 30 |
| 12 |
|
MFK Petržalka | 32 | 7 | 8 | 17 | 32:49 | -17 | 29 |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
