| 1. Ronde | 13.08.2021 | Real Zaragoza | - | UD Ibiza | 0:0 | ||||
| 2. Ronde | 20.08.2021 | Real Valladolid | - | Real Zaragoza | 2:0 | ||||
| 3. Ronde | 30.08.2021 | Real Zaragoza | - | FC Cartagena | 0:1 | ||||
| 4. Ronde | 05.09.2021 | AD Alcorcón | - | Real Zaragoza | 1:2 | ||||
| 6. Ronde | 18.09.2021 | Real Zaragoza | - | Real Sociedad B | 1:1 |  |
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| 8. Ronde | 02.10.2021 | Real Zaragoza | - | Real Oviedo | 0:0 | ||||
| 9. Ronde | 11.10.2021 | Real Zaragoza | - | SD Huesca | 0:0 | ||||
| 10. Ronde | 16.10.2021 | Málaga CF | - | Real Zaragoza | 1:1 | ||||
| 11. Ronde | 21.10.2021 | Real Zaragoza | - | SD Ponferradina | 1:1 | ||||
| 12. Ronde | 25.10.2021 | Girona FC | - | Real Zaragoza | 1:1 | ||||
| 13. Ronde | 31.10.2021 | Real Zaragoza | - | CD Mirandés | 1:1 | ||||
| 14. Ronde | 04.11.2021 | Burgos CF | - | Real Zaragoza | 0:1 | ||||
| 18. Ronde | 28.11.2021 | SD Amorebieta | - | Real Zaragoza | 1:1 | ||||
| 19. Ronde | 06.12.2021 | Real Zaragoza | - | SD Eibar | 1:0 | ||||
| 21. Ronde | 19.12.2021 | Real Zaragoza | - | CD Tenerife | 0:2 | ||||
| 22. Ronde | 02.01.2022 | CD Mirandés | - | Real Zaragoza | 2:0 |
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