| 5. Ronde | 18.10.2020 | Bisceglie | - | Palermo FC | 2:1 | ||||
| 7. Ronde | 04.11.2020 | US Catanzaro | - | Palermo FC | 1:1 | ||||
| 9. Ronde | 09.11.2020 | Palermo FC | - | Calcio Catania | 1:1 |  |
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| 10. Ronde | 12.11.2020 | Juve Stabia | - | Palermo FC | 1:2 | ||||
| 11. Ronde | 15.11.2020 | Palermo FC | - | Paganese Calcio | 2:1 | ||||
| 2. Ronde | 18.11.2020 | Palermo FC | - | Potenza | 1:0 | ||||
| 6. Ronde | 25.11.2020 | Palermo FC | - | FC Turris | 0:1 | ||||
| 13. Ronde | 29.11.2020 | Palermo FC | - | SS Monopoli 1966 | 3:0 |  |
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| 8. Ronde | 02.12.2020 | Palermo FC | - | Viterbese | 3:3 | |
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| 23. Ronde | 07.02.2021 | US Avellino | - | Palermo FC | 1:0 | ||||
| 26. Ronde | 21.02.2021 | Palermo FC | - | US Catanzaro | 1:2 | ||||
| 27. Ronde | 27.02.2021 | Viterbese | - | Palermo FC | 1:0 |  |
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| 29. Ronde | 07.03.2021 | Palermo FC | - | Juve Stabia | 2:4 | ||||
| 30. Ronde | 13.03.2021 | Paganese Calcio | - | Palermo FC | 0:1 | ||||
| 34. Ronde | 03.04.2021 | Casertana FC | - | Palermo FC | 2:3 |  |
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| 35. Ronde | 10.04.2021 | Palermo FC | - | Vibonese Calcio | 0:0 | ||||
| 33. Ronde | 14.04.2021 | Palermo FC | - | Foggia Calcio | 1:0 | ||||
| 36. Ronde | 18.04.2021 | SSC Bari | - | Palermo FC | 2:2 |
Italië