| 1. Ronde | 11.09.2021 | AC Perugia Calcio [A-jun] | - | Lazio Roma [A-jun] | 1:2 | ||||
| 2. Ronde | 18.09.2021 | Lazio Roma [A-jun] | - | FC Crotone [A-jun] | 6:2 | ||||
| 3. Ronde | 25.09.2021 | US Salernitana 1919 [A-jun] | - | Lazio Roma [A-jun] | 2:0 | ||||
| 10. Ronde | 27.11.2021 | Lazio Roma [A-jun] | - | Benevento Calcio [A-jun] | 0:1 | ||||
| 11. Ronde | 04.12.2021 | Cosenza Calcio [A-jun] | - | Lazio Roma [A-jun] | 1:2 | ||||
| 18. Ronde | 26.02.2022 | Lazio Roma [A-jun] | - | Reggina 1914 [A-jun] | 0:1 | ||||
| 19. Ronde | 05.03.2022 | Cesena FC [A-jun] | - | Lazio Roma [A-jun] | 3:1 | ||||
| 21. Ronde | 19.03.2022 | Spezia Calcio [A-jun] | - | Lazio Roma [A-jun] | 4:1 |
Italië