| 1. Ronde | 16.07.2021 | Godoy Cruz II | - | Rosario Central II | 1:1 |  |
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| 2. Ronde | 23.07.2021 | Defensa y Justicia II | - | Godoy Cruz II | 2:1 | ||||
| 3. Ronde | 27.07.2021 | Godoy Cruz II | - | Atlético Tucumán II | 2:2 | ||||
| 4. Ronde | 30.07.2021 | Colón de Santa Fe II | - | Godoy Cruz II | 0:0 | ||||
| 5. Ronde | 06.08.2021 | Godoy Cruz II | - | River Plate II | 0:1 | ||||
| 6. Ronde | 13.08.2021 | Lanús II | - | Godoy Cruz II | 5:1 | |
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| 7. Ronde | 20.08.2021 | Godoy Cruz II | - | Huracán II | 2:1 | ||||
| 8. Ronde | 26.08.2021 | Godoy Cruz II | - | Unión de Santa Fe II | 3:0 | ||||
| 10. Ronde | 05.09.2021 | Godoy Cruz II | - | Gimnasia de La Plata II | 3:0 | ||||
| 11. Ronde | 13.09.2021 | Aldosivi II | - | Godoy Cruz II | 1:2 | ||||
| 12. Ronde | 17.09.2021 | Godoy Cruz II | - | Sarmiento de Junín II | 0:0 | ||||
| 13. Ronde | 23.09.2021 | Independiente II | - | Godoy Cruz II | 0:0 | ||||
| 16. Ronde | 15.10.2021 | Godoy Cruz II | - | Central Córdoba SdE II | 3:0 | ||||
| 18. Ronde | 24.10.2021 | Godoy Cruz II | - | Banfield II | 2:0 | ||||
| 9. Ronde | 11.11.2021 | Vélez Sarsfield II | - | Godoy Cruz II | 3:0 | ||||
| 21. Ronde | 18.11.2021 | Argentinos Juniors II | - | Godoy Cruz II | 1:1 | ||||
| 23. Ronde | 27.11.2021 | Patronato de Paraná II | - | Godoy Cruz II | 1:0 |
Argentinië