| 11. Ronde | 10.09.2021 | Argentinos Juniors II | - | Patronato de Paraná II | 3:0 | ||||
| 12. Ronde | 16.09.2021 | Platense II | - | Argentinos Juniors II | 2:2 | ||||
| 13. Ronde | 27.09.2021 | Argentinos Juniors II | - | Racing Club II | 2:1 | ||||
| 14. Ronde | 01.10.2021 | Rosario Central II | - | Argentinos Juniors II | 0:2 | ||||
| 15. Ronde | 07.10.2021 | Argentinos Juniors II | - | Defensa y Justicia II | 0:0 | ||||
| 16. Ronde | 17.10.2021 | Atlético Tucumán II | - | Argentinos Juniors II | 0:0 | ||||
| 17. Ronde | 21.10.2021 | Argentinos Juniors II | - | Colón de Santa Fe II | 2:1 | ||||
| 18. Ronde | 26.10.2021 | River Plate II | - | Argentinos Juniors II | 0:3 | ||||
| 21. Ronde | 18.11.2021 | Argentinos Juniors II | - | Godoy Cruz II | 1:1 | ||||
| 22. Ronde | 25.11.2021 | Vélez Sarsfield II | - | Argentinos Juniors II | 1:1 | ||||
| 23. Ronde | 30.11.2021 | Argentinos Juniors II | - | Gimnasia de La Plata II | 1:2 | ||||
| 24. Ronde | 04.12.2021 | Aldosivi II | - | Argentinos Juniors II | 2:2 |
Paraguay