| 1. Ronde | 22.08.2021 | Lille OSC [A-jun] | - | Montfermeil FC [A-jun] | 1:0 | ||||
| 2. Ronde | 29.08.2021 | St-Pryvé St-Hilaire [A-jun] | - | Lille OSC [A-jun] | 1:2 | ||||
| 4. Ronde | 11.09.2021 | Lille OSC [A-jun] | - | Entente Feignies Aulnoye [A-jun] | 3:1 | ||||
| 5. Ronde | 19.09.2021 | Amiens SC [A-jun] | - | Lille OSC [A-jun] | 1:2 | ||||
| 6. Ronde | 26.09.2021 | Lille OSC [A-jun] | - | JA Drancy [A-jun] | 0:1 | ||||
| 7. Ronde | 03.10.2021 | Paris Saint-Germain [A-jun] | - | Lille OSC [A-jun] | 2:1 | ||||
| 8. Ronde | 10.10.2021 | Lille OSC [A-jun] | - | Havre AC [A-jun] | 1:1 | ||||
| 9. Ronde | 16.10.2021 | SM Caen [A-jun] | - | Lille OSC [A-jun] | 2:2 | ||||
| 11. Ronde | 14.11.2021 | Valenciennes FC [A-jun] | - | Lille OSC [A-jun] | 2:1 | ||||
| 12. Ronde | 20.11.2021 | Lille OSC [A-jun] | - | US Orléans [A-jun] | 1:4 | ||||
| 13. Ronde | 28.11.2021 | RC Lens [A-jun] | - | Lille OSC [A-jun] | 2:2 | ||||
| 14. Ronde | 05.12.2021 | Lille OSC [A-jun] | - | St-Pryvé St-Hilaire [A-jun] | 6:0 |
Frankrijk