| 2. Ronde | 16.09.2017 | AS Roma [A-jun] | - | Sassuolo Calcio [A-jun] | 1:1 |  |
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| 3. Ronde | 23.09.2017 | Sassuolo Calcio [A-jun] | - | Torino FC [A-jun] | 2:1 | ||||
| 4. Ronde | 30.09.2017 | Genoa CFC [A-jun] | - | Sassuolo Calcio [A-jun] | 3:1 | ||||
| 5. Ronde | 14.10.2017 | Sassuolo Calcio [A-jun] | - | Udinese Calcio [A-jun] | 3:1 | |
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| 6. Ronde | 21.10.2017 | Sampdoria [A-jun] | - | Sassuolo Calcio [A-jun] | 1:1 | ||||
| 7. Ronde | 28.10.2017 | Sassuolo Calcio [A-jun] | - | Chievo Verona [A-jun] | 4:2 | ||||
| 8. Ronde | 04.11.2017 | SSC Napoli [A-jun] | - | Sassuolo Calcio [A-jun] | 4:1 | ||||
| 12. Ronde | 09.12.2017 | Sassuolo Calcio [A-jun] | - | Atalanta [A-jun] | 0:2 | ||||
| 14. Ronde | 23.12.2017 | Sassuolo Calcio [A-jun] | - | Inter [A-jun] | 1:2 | ||||
| 16. Ronde | 20.01.2018 | AC Milan [A-jun] | - | Sassuolo Calcio [A-jun] | 2:1 | |
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| 17. Ronde | 27.01.2018 | Sassuolo Calcio [A-jun] | - | AS Roma [A-jun] | 3:3 | ||||
| 19. Ronde | 10.02.2018 | Sassuolo Calcio [A-jun] | - | Genoa CFC [A-jun] | 0:1 |  |
Italië