| 15. Ronde | 28.01.2022 | ACF Fiorentina [A-jun] | - | Bologna FC [A-jun] | 2:1 | ||||
| 16. Ronde | 02.02.2022 | Bologna FC [A-jun] | - | Hellas Verona [A-jun] | 1:0 |  |
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| 17. Ronde | 05.02.2022 | Bologna FC [A-jun] | - | Delfino Pescara [A-jun] | 2:0 | ||||
| 14. Ronde | 09.02.2022 | Bologna FC [A-jun] | - | AC Milan [A-jun] | 2:5 | ||||
| 18. Ronde | 13.02.2022 | SSC Napoli [A-jun] | - | Bologna FC [A-jun] | 1:2 | ||||
| 19. Ronde | 17.02.2022 | Bologna FC [A-jun] | - | US Lecce [A-jun] | 2:0 | ||||
| 20. Ronde | 21.02.2022 | Inter [A-jun] | - | Bologna FC [A-jun] | 1:0 | ||||
| 21. Ronde | 27.02.2022 | Bologna FC [A-jun] | - | Sampdoria [A-jun] | 2:2 | ||||
| 22. Ronde | 05.03.2022 | SPAL 2013 Ferrara [A-jun] | - | Bologna FC [A-jun] | 2:2 | ||||
| 24. Ronde | 12.03.2022 | Bologna FC [A-jun] | - | Genoa CFC [A-jun] | 1:0 | ||||
| 25. Ronde | 20.03.2022 | Cagliari Calcio [A-jun] | - | Bologna FC [A-jun] | 2:1 | ||||
| 30. Ronde | 19.04.2022 | Bologna FC [A-jun] | - | Torino FC [A-jun] | 1:0 | ||||
| 34. Ronde | 14.05.2022 | Delfino Pescara [A-jun] | - | Bologna FC [A-jun] | 1:1 | |
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