| 6. Ronde | 16.08.2021 | Racing Club II | - | Newell's Old Boys II | 1:1 | ||||
| 7. Ronde | 20.08.2021 | Newell's Old Boys II | - | Rosario Central II | 1:1 | ||||
| 16. Ronde | 14.10.2021 | Gimnasia de La Plata II | - | Newell's Old Boys II | 1:1 | ||||
| 17. Ronde | 18.10.2021 | Newell's Old Boys II | - | Aldosivi II | 1:0 | ||||
| 19. Ronde | 29.10.2021 | Newell's Old Boys II | - | Independiente II | 1:0 | ||||
| 20. Ronde | 05.11.2021 | Newell's Old Boys II | - | Unión de Santa Fe II | 1:2 | ||||
| 21. Ronde | 17.11.2021 | Arsenal de Sarandí II | - | Newell's Old Boys II | 0:3 | ||||
| 22. Ronde | 24.11.2021 | Newell's Old Boys II | - | Central Córdoba SdE II | 1:1 | ||||
| 23. Ronde | 30.11.2021 | Boca Juniors II | - | Newell's Old Boys II | 1:0 | ||||
| 25. Ronde | 10.12.2021 | San Lorenzo II | - | Newell's Old Boys II | 2:1 |
Argentinië