| 3. Ronde | 26.09.2021 | FC Schalke 04 [B-jun] | - | SC Paderborn 07 [B-jun] | 4:1 | ||||
| 5. Ronde | 10.10.2021 | FC Schalke 04 [B-jun] | - | 1. FC Köln [B-jun] | 2:0 | ||||
| 6. Ronde | 31.10.2021 | Wuppertaler SV [B-jun] | - | FC Schalke 04 [B-jun] | 1:7 | ||||
| 7. Ronde | 06.11.2021 | FC Schalke 04 [B-jun] | - | SG Unterrath 12/24 [B-jun] | 2:0 | ||||
| 8. Ronde | 27.11.2021 | Bor. Mönchengladbach [B-jun] | - | FC Schalke 04 [B-jun] | 0:1 | ||||
| 11. Ronde | 19.02.2022 | FC Schalke 04 [B-jun] | - | Arminia Bielefeld [B-jun] | 4:1 |  |
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| 12. Ronde | 27.02.2022 | Bayer Leverkusen [B-jun] | - | FC Schalke 04 [B-jun] | 0:5 | ||||
| 9. Ronde | 02.03.2022 | FC Schalke 04 [B-jun] | - | Borussia Dortmund [B-jun] | 2:0 | ||||
| 13. Ronde | 06.03.2022 | FC Schalke 04 [B-jun] | - | SV Lippstadt 08 [B-jun] | 5:0 | ||||
| 14. Ronde | 13.03.2022 | VfL Bochum [B-jun] | - | FC Schalke 04 [B-jun] | 0:2 | ||||
| 15. Ronde | 03.04.2022 | FC Schalke 04 [B-jun] | - | Preußen Münster [B-jun] | 1:2 | ||||
| 16. Ronde | 09.04.2022 | Alemannia Aachen [B-jun] | - | FC Schalke 04 [B-jun] | 0:4 | ||||
| 17. Ronde | 23.04.2022 | FC Schalke 04 [B-jun] | - | Fortuna Köln [B-jun] | 3:0 |
Duitsland
Congo DR