| 1. Ronde | 29.08.2021 | Cagliari Calcio [A-jun] | - | US Lecce [A-jun] | 1:1 | ||||
| 13. Ronde | 17.12.2021 | Cagliari Calcio [A-jun] | - | Hellas Verona [A-jun] | 2:1 | ||||
| 14. Ronde | 21.12.2021 | Juventus [A-jun] | - | Cagliari Calcio [A-jun] | 1:2 |  |
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| 24. Ronde | 12.03.2022 | Inter [A-jun] | - | Cagliari Calcio [A-jun] | 1:0 | ||||
| 25. Ronde | 20.03.2022 | Cagliari Calcio [A-jun] | - | Bologna FC [A-jun] | 2:1 | ||||
| 26. Ronde | 02.04.2022 | Cagliari Calcio [A-jun] | - | Atalanta [A-jun] | 3:4 | ||||
| 28. Ronde | 12.04.2022 | Cagliari Calcio [A-jun] | - | Torino FC [A-jun] | 1:0 | ||||
| 29. Ronde | 16.04.2022 | SSC Napoli [A-jun] | - | Cagliari Calcio [A-jun] | 1:2 | |
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| 30. Ronde | 21.04.2022 | Hellas Verona [A-jun] | - | Cagliari Calcio [A-jun] | 2:2 | ||||
| 32. Ronde | 01.05.2022 | AS Roma [A-jun] | - | Cagliari Calcio [A-jun] | 2:1 | ||||
| 31. Ronde | 11.05.2022 | Cagliari Calcio [A-jun] | - | Juventus [A-jun] | 2:0 | ||||
| 34. Ronde | 15.05.2022 | Empoli FC [A-jun] | - | Cagliari Calcio [A-jun] | 1:0 |
Italië