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| 16.04.2021 | 15:00 | Estudiantes II | - | Gimnasia de La Plata II | 2:0 (1:0) | |
| 15:00 | Independiente II | - | Defensa y Justicia II | 2:3 (1:1) | ||
| 15:00 | Boca Juniors II | - | Atlético Tucumán II | 3:1 (2:1) | ||
| 15:00 | Vélez Sarsfield II | - | Huracán II | 2:0 (1:0) | ||
| 15:00 | Talleres de Córdoba II | - | Unión de Santa Fe II | 0:0 (0:0) | ||
| 15:00 | Newell's Old Boys II | - | Patronato de Paraná II | 1:0 (0:0) | ||
| 15:00 | Colón de Santa Fe II | - | Godoy Cruz II | 1:2 (0:1) | ||
| 15:00 | Central Córdoba SdE II | - | River Plate II | 1:2 (0:2) | ||
| 15:00 | San Lorenzo II | - | Argentinos Juniors II | 2:2 (2:1) | ||
| 15:00 | Banfield II | - | Platense II | 2:2 (2:2) | ||
| 15:00 | Aldosivi II | - | Rosario Central II | 1:3 (0:0) | ||
| 15:00 | Arsenal de Sarandí II | - | Racing Club II | 1:1 (1:0) | ||
| 18:00 | Sarmiento de Junín II | - | Lanús II | 4:1 (2:1) |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
River Plate II | 10 | 8 | 2 | 0 | 20:5 | 15 | 26 |
| 2 |
|
Argentinos Juniors II | 10 | 5 | 4 | 1 | 11:4 | 7 | 19 |
| 3 |
|
Estudiantes II | 10 | 5 | 2 | 3 | 13:10 | 3 | 17 |
| 4 |
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Godoy Cruz II | 10 | 4 | 4 | 2 | 11:7 | 4 | 16 |
| 5 |
|
Aldosivi II | 10 | 5 | 0 | 5 | 16:12 | 4 | 15 |
| 6 |
|
Rosario Central II | 10 | 3 | 5 | 2 | 14:8 | 6 | 14 |
| 7 |
|
Banfield II | 10 | 3 | 5 | 2 | 12:11 | 1 | 14 |
| 8 |
|
Racing Club II | 10 | 4 | 2 | 4 | 10:11 | -1 | 14 |
| 9 |
|
Platense II | 10 | 2 | 4 | 4 | 15:14 | 1 | 10 |
| 10 |
|
San Lorenzo II | 10 | 2 | 4 | 4 | 12:15 | -3 | 10 |
| 11 |
|
Colón de Santa Fe II | 10 | 1 | 4 | 5 | 6:17 | -11 | 7 |
| 12 |
|
Central Córdoba SdE II | 10 | 2 | 1 | 7 | 7:22 | -15 | 7 |
| 13 |
|
Arsenal de Sarandí II | 10 | 0 | 6 | 4 | 10:19 | -9 | 6 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors II | 10 | 6 | 3 | 1 | 19:10 | 9 | 21 |
| 2 |
|
Sarmiento de Junín II | 10 | 6 | 2 | 2 | 24:17 | 7 | 20 |
| 3 |
|
Independiente II | 10 | 5 | 2 | 3 | 21:16 | 5 | 17 |
| 4 |
|
Newell's Old Boys II | 10 | 5 | 1 | 4 | 19:17 | 2 | 16 |
| 5 |
|
Unión de Santa Fe II | 10 | 4 | 2 | 4 | 16:16 | 0 | 14 |
| 6 |
|
Huracán II | 10 | 3 | 5 | 2 | 15:16 | -1 | 14 |
| 7 |
|
Defensa y Justicia II | 10 | 3 | 4 | 3 | 17:16 | 1 | 13 |
| 8 |
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Vélez Sarsfield II | 10 | 3 | 3 | 4 | 14:13 | 1 | 12 |
| 9 |
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Gimnasia de La Plata II | 10 | 3 | 3 | 4 | 12:13 | -1 | 12 |
| 10 |
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Atlético Tucumán II | 10 | 3 | 2 | 5 | 15:17 | -2 | 11 |
| 11 |
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Patronato de Paraná II | 10 | 2 | 4 | 4 | 8:14 | -6 | 10 |
| 12 |
|
Lanús II | 10 | 2 | 2 | 6 | 18:25 | -7 | 8 |
| 13 |
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Talleres de Córdoba II | 10 | 1 | 4 | 5 | 11:21 | -10 | 7 |
| Play-offs | |
| Play-offs |
