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| 11.04.1999 | 18:00 | Sint-Truidense VV | - | KV Kortrijk | 2:2 (0:0) | |
| 05.05.1999 | 20:00 | KVC Westerlo | - | Excelsior Mouscron | 1:1 (0:1) | |
| 20:00 | Lommelse SK | - | KRC Genk | 0:3 (0:2) | ||
| 20:00 | Sporting Lokeren | - | KV Oostende | 1:2 (1:1) | ||
| 20:00 | Lierse SK | - | K.S.C. Eendracht Aalst | 3:1 (2:0) | ||
| 20:00 | Germinal Beerschot | - | RSC Charleroi | 2:0 (2:0) | ||
| 20:00 | KRC Harelbeke | - | Standard Luik | 1:1 (0:0) | ||
| 20:00 | Club Brugge KV | - | KSK Beveren | 3:1 (2:0) | ||
| 20:00 | RSC Anderlecht | - | KAA Gent | 4:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk | 32 | 21 | 7 | 4 | 70:32 | 38 | 70 |
| 2 |
|
Club Brugge KV | 32 | 21 | 5 | 6 | 60:33 | 27 | 68 |
| 3 |
|
RSC Anderlecht | 32 | 19 | 7 | 6 | 68:36 | 32 | 64 |
| 4 |
|
Excelsior Mouscron | 32 | 18 | 8 | 6 | 73:46 | 27 | 62 |
| 5 |
|
Standard Luik | 32 | 17 | 3 | 12 | 53:40 | 13 | 54 |
| 6 |
|
Sporting Lokeren | 32 | 16 | 6 | 10 | 64:55 | 9 | 54 |
| 7 |
|
Sint-Truidense VV | 32 | 14 | 8 | 10 | 50:43 | 7 | 50 |
| 8 |
|
Lierse SK | 32 | 14 | 6 | 12 | 63:47 | 16 | 48 |
| 9 |
|
Germinal Beerschot | 32 | 14 | 6 | 12 | 46:43 | 3 | 48 |
| 10 |
|
KAA Gent | 32 | 13 | 9 | 10 | 51:58 | -7 | 48 |
| 11 |
|
KRC Harelbeke | 32 | 10 | 10 | 12 | 43:44 | -1 | 40 |
| 12 |
|
KVC Westerlo | 32 | 11 | 6 | 15 | 52:56 | -4 | 39 |
| 13 |
|
K.S.C. Eendracht Aalst | 32 | 8 | 7 | 17 | 43:65 | -22 | 31 |
| 14 |
|
RSC Charleroi | 32 | 6 | 11 | 15 | 37:51 | -14 | 29 |
| 15 |
|
KSK Beveren | 32 | 7 | 5 | 20 | 30:58 | -28 | 26 |
| 16 |
|
Lommelse SK | 32 | 6 | 7 | 19 | 30:51 | -21 | 25 |
| 17 |
|
KV Kortrijk | 32 | 5 | 7 | 20 | 44:77 | -33 | 22 |
| 18 |
|
KV Oostende | 32 | 4 | 10 | 18 | 27:69 | -42 | 22 |
