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| 25.04.1981 | K Waterschei SV Thor Genk | - | Club Brugge KV | 2:2 | ||
| KSV Waregem | - | FC Beringen | 2:1 | |||
| Standard Luik | - | K. Beerschot VAV | 3:0 | |||
| KAA Gent | - | RFC Liège | 3:1 | |||
| Cercle Brugge | - | Lierse SK | 2:1 | |||
| KSK Beveren | - | KV Kortrijk | 1:1 | |||
| Berchem Sport | - | RWD Molenbeek | 1:3 | |||
| Royal Antwerp FC | - | KFC Winterslag | 1:1 | |||
| RSC Anderlecht | - | Sporting Lokeren | 3:1 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RSC Anderlecht | 31 | 23 | 5 | 3 | 71:22 | 49 | 51:11 |
| 2 |
|
Sporting Lokeren | 31 | 17 | 6 | 8 | 64:35 | 29 | 40:22 |
| 3 |
|
KSK Beveren | 31 | 16 | 8 | 7 | 48:29 | 19 | 40:22 |
| 4 |
|
Standard Luik | 31 | 17 | 5 | 9 | 60:41 | 19 | 39:23 |
| 5 |
|
Club Brugge KV | 31 | 15 | 5 | 11 | 70:49 | 21 | 35:27 |
| 6 |
|
KFC Winterslag | 31 | 14 | 6 | 11 | 42:40 | 2 | 34:28 |
| 7 |
|
KAA Gent | 31 | 12 | 8 | 11 | 48:42 | 6 | 32:30 |
| 8 |
|
RWD Molenbeek | 31 | 13 | 6 | 12 | 44:44 | 0 | 32:30 |
| 9 |
|
Royal Antwerp FC | 31 | 10 | 11 | 10 | 39:47 | -8 | 31:31 |
| 10 |
|
Lierse SK | 31 | 10 | 11 | 10 | 54:47 | 7 | 31:31 |
| 11 |
|
KSV Waregem | 31 | 10 | 10 | 11 | 37:39 | -2 | 30:32 |
| 12 |
|
RFC Liège | 31 | 9 | 8 | 14 | 44:42 | 2 | 26:36 |
| 13 |
|
Cercle Brugge | 31 | 10 | 6 | 15 | 45:61 | -16 | 26:36 |
| 14 |
|
KV Kortrijk | 31 | 9 | 8 | 14 | 36:53 | -17 | 26:36 |
| 15 |
|
K Waterschei SV Thor Genk | 31 | 9 | 5 | 17 | 48:69 | -21 | 23:39 |
| 16 |
|
K. Beerschot VAV | 31 | 8 | 6 | 17 | 33:50 | -17 | 22:40 |
| 17 |
|
FC Beringen | 31 | 7 | 7 | 17 | 34:59 | -25 | 21:41 |
| 18 |
|
Berchem Sport | 31 | 5 | 9 | 17 | 27:75 | -48 | 19:43 |
