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| 20.03.2009 | 20:30 | KV Kortrijk | - | Club Brugge KV | 2:3 (1:2) | |
| 21.03.2009 | 20:00 | Cercle Brugge | - | Excelsior Mouscron | 0:1 (0:1) | |
| 20:00 | KRC Genk | - | AFC Tubize | 3:0 (3:0) | ||
| 20:00 | RSC Anderlecht | - | Germinal Beerschot | 2:0 (0:0) | ||
| 20:00 | KVC Westerlo | - | FCV Dender EH | 3:1 (1:1) | ||
| 20:00 | KSV Roeselare | - | KV Mechelen | 1:0 (0:0) | ||
| 20:00 | RAEC Mons | - | Sporting Lokeren | 0:2 (0:0) | ||
| 22.03.2009 | 18:00 | KAA Gent | - | SV Zulte Waregem | 1:0 (0:0) | |
| 20:30 | Sporting Charleroi | - | Standard Luik | 1:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RSC Anderlecht | 27 | 19 | 3 | 5 | 63:28 | 35 | 60 |
| 2 |
|
Standard Luik | 27 | 18 | 4 | 5 | 52:24 | 28 | 58 |
| 3 |
|
Club Brugge KV | 27 | 15 | 5 | 7 | 48:38 | 10 | 50 |
| 4 |
|
KRC Genk | 27 | 14 | 4 | 9 | 43:37 | 6 | 46 |
| 5 |
|
KAA Gent | 27 | 13 | 6 | 8 | 55:36 | 19 | 45 |
| 6 |
|
KVC Westerlo | 27 | 12 | 7 | 8 | 33:29 | 4 | 43 |
| 7 |
|
Sporting Lokeren | 27 | 10 | 11 | 6 | 33:24 | 9 | 41 |
| 8 |
|
SV Zulte Waregem | 27 | 11 | 6 | 10 | 40:32 | 8 | 39 |
| 9 |
|
Excelsior Mouscron | 27 | 10 | 8 | 9 | 35:33 | 2 | 38 |
| 10 |
|
Germinal Beerschot | 27 | 9 | 9 | 9 | 36:31 | 5 | 36 |
| 11 |
|
KV Mechelen | 27 | 9 | 9 | 9 | 37:42 | -5 | 36 |
| 12 |
|
Cercle Brugge | 27 | 10 | 5 | 12 | 36:43 | -7 | 35 |
| 13 |
|
Sporting Charleroi | 27 | 8 | 7 | 12 | 33:40 | -7 | 31 |
| 14 |
|
KV Kortrijk | 27 | 7 | 9 | 11 | 28:42 | -14 | 30 |
| 15 |
|
FCV Dender EH | 27 | 6 | 6 | 15 | 35:49 | -14 | 24 |
| 16 |
|
KSV Roeselare | 27 | 6 | 6 | 15 | 27:47 | -20 | 24 |
| 17 |
|
AFC Tubize | 27 | 5 | 3 | 19 | 26:67 | -41 | 18 |
| 18 |
|
RAEC Mons | 27 | 3 | 8 | 16 | 26:44 | -18 | 17 |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
