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| 19.09.2008 | 20:30 | RSC Anderlecht | - | Sporting Charleroi | 2:0 (0:0) | |
| 20.09.2008 | 20:00 | KSV Roeselare | - | Sporting Lokeren | 0:1 (0:0) | |
| 20:00 | Cercle Brugge | - | Germinal Beerschot | 1:0 (1:0) | ||
| 20:00 | KAA Gent | - | KV Mechelen | 1:2 (1:1) | ||
| 20:00 | KVC Westerlo | - | Excelsior Mouscron | 0:0 (0:0) | ||
| 20:00 | KV Kortrijk | - | RAEC Mons | 1:0 (1:0) | ||
| 20:00 | FCV Dender EH | - | SV Zulte Waregem | 2:0 (1:0) | ||
| 21.09.2008 | 18:00 | AFC Tubize | - | Standard Luik | 0:1 (0:1) | |
| 20:30 | KRC Genk | - | Club Brugge KV | 0:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RSC Anderlecht | 5 | 4 | 1 | 0 | 13:3 | 10 | 13 |
| 2 |
|
Standard Luik | 5 | 4 | 1 | 0 | 10:2 | 8 | 13 |
| 3 |
|
Excelsior Mouscron | 5 | 4 | 1 | 0 | 11:5 | 6 | 13 |
| 4 |
|
Club Brugge KV | 5 | 3 | 2 | 0 | 9:3 | 6 | 11 |
| 5 |
|
Sporting Lokeren | 5 | 2 | 2 | 1 | 6:3 | 3 | 8 |
| 6 |
|
KVC Westerlo | 5 | 2 | 2 | 1 | 3:4 | -1 | 8 |
| 7 |
|
KRC Genk | 5 | 2 | 1 | 2 | 6:6 | 0 | 7 |
| 8 |
|
KV Kortrijk | 5 | 2 | 1 | 2 | 5:9 | -4 | 7 |
| 9 |
|
KAA Gent | 5 | 2 | 1 | 2 | 12:8 | 4 | 7 |
| 10 |
|
Cercle Brugge | 5 | 2 | 0 | 3 | 6:9 | -3 | 6 |
| 11 |
|
Sporting Charleroi | 5 | 2 | 0 | 3 | 4:7 | -3 | 6 |
| 12 |
|
Germinal Beerschot | 5 | 1 | 2 | 2 | 5:4 | 1 | 5 |
| 13 |
|
FCV Dender EH | 5 | 1 | 2 | 2 | 6:7 | -1 | 5 |
| 14 |
|
KV Mechelen | 5 | 1 | 2 | 2 | 4:7 | -3 | 5 |
| 15 |
|
SV Zulte Waregem | 5 | 1 | 1 | 3 | 3:7 | -4 | 4 |
| 16 |
|
RAEC Mons | 5 | 1 | 0 | 4 | 5:11 | -6 | 3 |
| 17 |
|
KSV Roeselare | 5 | 0 | 2 | 3 | 3:8 | -5 | 2 |
| 18 |
|
AFC Tubize | 5 | 0 | 1 | 4 | 3:11 | -8 | 1 |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
