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| 24.10.2008 | 20:30 | KV Kortrijk | - | Excelsior Mouscron | 2:2 (1:1) | |
| 25.10.2008 | 20:00 | RSC Anderlecht | - | KV Mechelen | 7:1 (4:1) | |
| 20:00 | KSV Roeselare | - | SV Zulte Waregem | 0:3 (0:1) | ||
| 20:00 | RAEC Mons | - | Germinal Beerschot | 0:0 (0:0) | ||
| 20:00 | KVC Westerlo | - | AFC Tubize | 4:1 (2:0) | ||
| 20:00 | Cercle Brugge | - | FCV Dender EH | 1:2 (1:1) | ||
| 20:00 | Sporting Charleroi | - | Sporting Lokeren | 1:1 (1:1) | ||
| 26.10.2008 | 18:00 | KAA Gent | - | Club Brugge KV | 3:0 (0:0) | |
| 20:30 | KRC Genk | - | Standard Luik | 0:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Standard Luik | 9 | 6 | 2 | 1 | 15:8 | 7 | 20 |
| 2 |
|
Club Brugge KV | 9 | 6 | 2 | 1 | 15:7 | 8 | 20 |
| 3 |
|
RSC Anderlecht | 9 | 6 | 1 | 2 | 23:11 | 12 | 19 |
| 4 |
|
Excelsior Mouscron | 9 | 5 | 2 | 2 | 17:11 | 6 | 17 |
| 5 |
|
KRC Genk | 9 | 5 | 2 | 2 | 14:10 | 4 | 17 |
| 6 |
|
KVC Westerlo | 9 | 5 | 2 | 2 | 13:10 | 3 | 17 |
| 7 |
|
KAA Gent | 9 | 4 | 3 | 2 | 19:11 | 8 | 15 |
| 8 |
|
Sporting Lokeren | 9 | 3 | 5 | 1 | 11:6 | 5 | 14 |
| 9 |
|
SV Zulte Waregem | 9 | 4 | 1 | 4 | 13:10 | 3 | 13 |
| 10 |
|
KV Kortrijk | 9 | 3 | 3 | 3 | 9:14 | -5 | 12 |
| 11 |
|
Sporting Charleroi | 9 | 3 | 2 | 4 | 9:12 | -3 | 11 |
| 12 |
|
Cercle Brugge | 9 | 3 | 1 | 5 | 13:16 | -3 | 10 |
| 13 |
|
Germinal Beerschot | 9 | 1 | 5 | 3 | 8:8 | 0 | 8 |
| 14 |
|
RAEC Mons | 9 | 2 | 2 | 5 | 9:14 | -5 | 8 |
| 15 |
|
FCV Dender EH | 9 | 2 | 2 | 5 | 12:18 | -6 | 8 |
| 16 |
|
KV Mechelen | 9 | 2 | 2 | 5 | 11:20 | -9 | 8 |
| 17 |
|
AFC Tubize | 9 | 1 | 1 | 7 | 6:18 | -12 | 4 |
| 18 |
|
KSV Roeselare | 9 | 0 | 2 | 7 | 3:16 | -13 | 2 |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
