| 2. Ronde | 23.07.2021 | Banfield II | - | Boca Juniors II | 1:3 | ||||
| 4. Ronde | 02.08.2021 | Talleres de Córdoba II | - | Boca Juniors II | 1:1 | ||||
| 5. Ronde | 06.08.2021 | Boca Juniors II | - | Argentinos Juniors II | 0:1 | ||||
| 10. Ronde | 03.09.2021 | Rosario Central II | - | Boca Juniors II | 1:3 | ||||
| 12. Ronde | 18.09.2021 | Atlético Tucumán II | - | Boca Juniors II | 1:1 | ||||
| 13. Ronde | 24.09.2021 | Boca Juniors II | - | Colón de Santa Fe II | 3:1 | ||||
| 14. Ronde | 01.10.2021 | River Plate II | - | Boca Juniors II | 0:3 | ||||
| 19. Ronde | 29.10.2021 | Boca Juniors II | - | Gimnasia de La Plata II | 1:1 | ||||
| 20. Ronde | 04.11.2021 | Aldosivi II | - | Boca Juniors II | 1:1 | ||||
| 3. Ronde | 11.11.2021 | Boca Juniors II | - | San Lorenzo II | 4:1 | ||||
| 21. Ronde | 18.11.2021 | Boca Juniors II | - | Sarmiento de Junín II | 4:4 | ||||
| 22. Ronde | 24.11.2021 | Independiente II | - | Boca Juniors II | 0:0 | ||||
| 23. Ronde | 30.11.2021 | Boca Juniors II | - | Newell's Old Boys II | 1:0 | ||||
| 24. Ronde | 04.12.2021 | Arsenal de Sarandí II | - | Boca Juniors II | 1:2 | ||||
| 25. Ronde | 11.12.2021 | Boca Juniors II | - | Central Córdoba SdE II | 7:0 |
Argentinië