| 4. Ronde | 04.09.2021 | SD Eibar | - | CD Leganés | 1:1 | ||||
| 5. Ronde | 11.09.2021 | Real Sociedad B | - | SD Eibar | 2:3 |  |
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| 6. Ronde | 19.09.2021 | SD Eibar | - | Sporting Gijón | 3:2 | ||||
| 7. Ronde | 25.09.2021 | SD Amorebieta | - | SD Eibar | 1:1 | ||||
| 8. Ronde | 03.10.2021 | SD Eibar | - | UD Ibiza | 3:1 | ||||
| 12. Ronde | 22.10.2021 | SD Eibar | - | FC Cartagena | 2:1 | ||||
| 14. Ronde | 03.11.2021 | SD Eibar | - | Real Oviedo | 1:0 |  |
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| 15. Ronde | 06.11.2021 | CF Fuenlabrada | - | SD Eibar | 0:0 | |
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| 16. Ronde | 13.11.2021 | SD Eibar | - | AD Alcorcón | 2:1 | |
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| 17. Ronde | 21.11.2021 | CD Lugo | - | SD Eibar | 2:2 | ||||
| 18. Ronde | 29.11.2021 | SD Eibar | - | Girona FC | 4:2 | |
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| 20. Ronde | 11.12.2021 | SD Eibar | - | Málaga CF | 2:2 | ||||
| 21. Ronde | 18.12.2021 | UD Las Palmas | - | SD Eibar | 0:1 | ||||
| 22. Ronde | 31.12.2021 | SD Eibar | - | Real Sociedad B | 3:2 | ||||
| 23. Ronde | 10.01.2022 | Real Oviedo | - | SD Eibar | 1:1 | ||||
| 35. Ronde | 10.04.2022 | UD Ibiza | - | SD Eibar | 2:0 | ||||
| 36. Ronde | 15.04.2022 | SD Eibar | - | UD Las Palmas | 2:2 | |
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