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| 09.07.2022 | 01:00 | Rosario Central | - | Sarmiento de Junín | 1:0 (0:0) | |
| 18:00 | Patronato de Paraná | - | Arsenal de Sarandí | 0:1 (0:1) | ||
| 20:30 | San Lorenzo | - | Boca Juniors | 2:1 (1:1) | ||
| 23:00 | Banfield | - | Unión de Santa Fe | 2:3 (1:2) | ||
| 10.07.2022 | 01:30 | Platense | - | Newell's Old Boys | 1:1 (0:1) | |
| 01:30 | Talleres de Córdoba | - | Barracas Central | 0:2 (0:1) | ||
| 18:00 | Estudiantes | - | Central Córdoba SdE | 2:2 (2:1) | ||
| 20:30 | Racing Club | - | Independiente | 1:0 (1:0) | ||
| 23:00 | Atlético Tucumán | - | Gimnasia de La Plata | 2:0 (1:0) | ||
| 23:00 | Lanús | - | Huracán | 2:3 (2:1) | ||
| 11.07.2022 | 01:30 | River Plate | - | Godoy Cruz | 0:2 (0:2) | |
| 12.07.2022 | 00:00 | Colón de Santa Fe | - | Vélez Sarsfield | 2:1 (1:1) | |
| 00:00 | Defensa y Justicia | - | Aldosivi | 3:2 (0:2) | ||
| 02:30 | Argentinos Juniors | - | Tigre | 2:1 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Newell's Old Boys | 7 | 4 | 3 | 0 | 9:4 | 5 | 15 |
| 2 |
|
Gimnasia de La Plata | 7 | 4 | 2 | 1 | 9:5 | 4 | 14 |
| 3 |
|
Huracán | 7 | 4 | 2 | 1 | 10:7 | 3 | 14 |
| 4 |
|
Racing Club | 7 | 4 | 1 | 2 | 12:6 | 6 | 13 |
| 5 |
|
Godoy Cruz | 7 | 4 | 1 | 2 | 9:5 | 4 | 13 |
| 6 |
|
Platense | 7 | 3 | 4 | 0 | 8:4 | 4 | 13 |
| 7 |
|
Atlético Tucumán | 7 | 3 | 4 | 0 | 7:3 | 4 | 13 |
| 8 |
|
Argentinos Juniors | 7 | 4 | 1 | 2 | 9:7 | 2 | 13 |
| 9 |
|
Unión de Santa Fe | 7 | 4 | 1 | 2 | 14:13 | 1 | 13 |
| 10 |
|
Banfield | 7 | 3 | 2 | 2 | 10:7 | 3 | 11 |
| 11 |
|
San Lorenzo | 7 | 2 | 4 | 1 | 10:8 | 2 | 10 |
| 12 |
|
Arsenal de Sarandí | 7 | 2 | 4 | 1 | 9:8 | 1 | 10 |
| 13 |
|
Barracas Central | 7 | 2 | 3 | 2 | 9:9 | 0 | 9 |
| 14 |
|
Boca Juniors | 7 | 3 | 0 | 4 | 12:13 | -1 | 9 |
| 15 |
|
River Plate | 7 | 2 | 2 | 3 | 9:8 | 1 | 8 |
| 16 |
|
Central Córdoba SdE | 7 | 2 | 2 | 3 | 8:9 | -1 | 8 |
| 17 |
|
Colón de Santa Fe | 7 | 2 | 2 | 3 | 6:7 | -1 | 8 |
|
Sarmiento de Junín | 7 | 2 | 2 | 3 | 6:7 | -1 | 8 | |
| 19 |
|
Estudiantes | 7 | 2 | 2 | 3 | 8:10 | -2 | 8 |
|
Patronato de Paraná | 7 | 2 | 2 | 3 | 8:10 | -2 | 8 | |
| 21 |
|
Defensa y Justicia | 7 | 1 | 4 | 2 | 7:8 | -1 | 7 |
| 22 |
|
Independiente | 7 | 2 | 1 | 4 | 7:11 | -4 | 7 |
| 23 |
|
Rosario Central | 7 | 2 | 1 | 4 | 3:7 | -4 | 7 |
| 24 |
|
Tigre | 7 | 1 | 3 | 3 | 9:12 | -3 | 6 |
| 25 |
|
Vélez Sarsfield | 7 | 1 | 2 | 4 | 5:8 | -3 | 5 |
| 26 |
|
Talleres de Córdoba | 7 | 1 | 2 | 4 | 4:8 | -4 | 5 |
| 27 |
|
Lanús | 7 | 1 | 2 | 4 | 6:11 | -5 | 5 |
| 28 |
|
Aldosivi | 7 | 1 | 1 | 5 | 5:13 | -8 | 4 |
