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| 02.07.2022 | 00:00 | Central Córdoba SdE | - | Argentinos Juniors | 1:2 (0:0) | |
| 02:30 | Boca Juniors | - | Banfield | 0:3 (0:3) | ||
| 20:30 | Tigre | - | Talleres de Córdoba | 1:1 (1:0) | ||
| 23:00 | Godoy Cruz | - | Colón de Santa Fe | 1:0 (0:0) | ||
| 23:00 | Vélez Sarsfield | - | Atlético Tucumán | 0:1 (0:1) | ||
| 03.07.2022 | 01:30 | Gimnasia de La Plata | - | Defensa y Justicia | 1:0 (0:0) | |
| 18:00 | Unión de Santa Fe | - | Lanús | 3:0 (1:0) | ||
| 20:00 | Barracas Central | - | San Lorenzo | 2:1 (2:1) | ||
| 23:00 | Sarmiento de Junín | - | Racing Club | 1:1 (0:0) | ||
| 04.07.2022 | 02:00 | Huracán | - | River Plate | 3:2 (1:0) | |
| 22:00 | Arsenal de Sarandí | - | Estudiantes | 2:1 (1:1) | ||
| 05.07.2022 | 00:00 | Aldosivi | - | Rosario Central | 2:1 (1:0) | |
| 00:00 | Newell's Old Boys | - | Patronato de Paraná | 2:2 (2:0) | ||
| 02:30 | Independiente | - | Platense | 1:3 (1:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Gimnasia de La Plata | 6 | 4 | 2 | 0 | 9:3 | 6 | 14 |
| 2 |
|
Newell's Old Boys | 6 | 4 | 2 | 0 | 8:3 | 5 | 14 |
| 3 |
|
Platense | 6 | 3 | 3 | 0 | 7:3 | 4 | 12 |
| 4 |
|
Banfield | 6 | 3 | 2 | 1 | 8:4 | 4 | 11 |
| 5 |
|
Huracán | 6 | 3 | 2 | 1 | 7:5 | 2 | 11 |
| 6 |
|
Racing Club | 6 | 3 | 1 | 2 | 11:6 | 5 | 10 |
| 7 |
|
Godoy Cruz | 6 | 3 | 1 | 2 | 7:5 | 2 | 10 |
| 8 |
|
Atlético Tucumán | 6 | 2 | 4 | 0 | 5:3 | 2 | 10 |
| 9 |
|
Argentinos Juniors | 6 | 3 | 1 | 2 | 7:6 | 1 | 10 |
| 10 |
|
Unión de Santa Fe | 6 | 3 | 1 | 2 | 11:11 | 0 | 10 |
| 11 |
|
Boca Juniors | 6 | 3 | 0 | 3 | 11:11 | 0 | 9 |
| 12 |
|
River Plate | 6 | 2 | 2 | 2 | 9:6 | 3 | 8 |
| 13 |
|
Sarmiento de Junín | 6 | 2 | 2 | 2 | 6:6 | 0 | 8 |
| 14 |
|
Patronato de Paraná | 6 | 2 | 2 | 2 | 8:9 | -1 | 8 |
| 15 |
|
San Lorenzo | 6 | 1 | 4 | 1 | 8:7 | 1 | 7 |
| 16 |
|
Arsenal de Sarandí | 6 | 1 | 4 | 1 | 8:8 | 0 | 7 |
| 17 |
|
Central Córdoba SdE | 6 | 2 | 1 | 3 | 6:7 | -1 | 7 |
| 18 |
|
Estudiantes | 6 | 2 | 1 | 3 | 6:8 | -2 | 7 |
| 19 |
|
Independiente | 6 | 2 | 1 | 3 | 7:10 | -3 | 7 |
| 20 |
|
Tigre | 6 | 1 | 3 | 2 | 8:10 | -2 | 6 |
| 21 |
|
Barracas Central | 6 | 1 | 3 | 2 | 7:9 | -2 | 6 |
| 22 |
|
Colón de Santa Fe | 6 | 1 | 2 | 3 | 4:6 | -2 | 5 |
|
Talleres de Córdoba | 6 | 1 | 2 | 3 | 4:6 | -2 | 5 | |
|
Vélez Sarsfield | 6 | 1 | 2 | 3 | 4:6 | -2 | 5 | |
| 25 |
|
Lanús | 6 | 1 | 2 | 3 | 4:8 | -4 | 5 |
| 26 |
|
Defensa y Justicia | 6 | 0 | 4 | 2 | 4:6 | -2 | 4 |
| 27 |
|
Rosario Central | 6 | 1 | 1 | 4 | 2:7 | -5 | 4 |
| 28 |
|
Aldosivi | 6 | 1 | 1 | 4 | 3:10 | -7 | 4 |
