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| 04.04.2009 | 20:00 | Recreativo Huelva | - | Sevilla FC | 0:1 (0:1) | |
| 20:00 | Real Valladolid | - | FC Barcelona | 0:1 (0:1) | ||
| 20:00 | UD Almería | - | Villarreal CF | 3:0 (3:0) | ||
| 20:00 | Athletic Bilbao | - | RCD Mallorca | 2:1 (1:0) | ||
| 20:00 | Real Betis | - | CD Numancia | 3:3 (1:1) | ||
| 22:00 | Málaga CF | - | Real Madrid | 0:1 (0:0) | ||
| 05.04.2009 | 17:00 | Atlético Madrid | - | CA Osasuna | 2:4 (1:2) | |
| 17:00 | Espanyol | - | Deportivo La Coruña | 3:1 (2:1) | ||
| 19:00 | Valencia CF | - | Getafe CF | 4:1 (2:0) | ||
| 21:00 | Sporting Gijón | - | Racing Santander | 0:2 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 29 | 23 | 3 | 3 | 85:24 | 61 | 72 |
| 2 |
|
Real Madrid | 29 | 21 | 3 | 5 | 67:31 | 36 | 66 |
| 3 |
|
Sevilla FC | 29 | 17 | 6 | 6 | 43:26 | 17 | 57 |
| 4 |
|
Villarreal CF | 29 | 13 | 9 | 7 | 45:40 | 5 | 48 |
| 5 |
|
Valencia CF | 29 | 13 | 7 | 9 | 52:41 | 11 | 46 |
| 6 |
|
Atlético Madrid | 29 | 12 | 7 | 10 | 58:47 | 11 | 43 |
| 7 |
|
Málaga CF | 29 | 12 | 7 | 10 | 45:47 | -2 | 43 |
| 8 |
|
Deportivo La Coruña | 29 | 12 | 7 | 10 | 38:40 | -2 | 43 |
| 9 |
|
Real Valladolid | 29 | 12 | 3 | 14 | 42:47 | -5 | 39 |
| 10 |
|
Racing Santander | 29 | 9 | 9 | 11 | 36:35 | 1 | 36 |
| 11 |
|
Athletic Bilbao | 29 | 9 | 7 | 13 | 39:49 | -10 | 34 |
| 12 |
|
UD Almería | 29 | 9 | 7 | 13 | 36:46 | -10 | 34 |
| 13 |
|
Sporting Gijón | 29 | 11 | 0 | 18 | 36:61 | -25 | 33 |
| 14 |
|
CA Osasuna | 29 | 7 | 11 | 11 | 32:35 | -3 | 32 |
| 15 |
|
RCD Mallorca | 29 | 8 | 8 | 13 | 34:48 | -14 | 32 |
| 16 |
|
Real Betis | 29 | 7 | 10 | 12 | 41:47 | -6 | 31 |
| 17 |
|
Getafe CF | 29 | 7 | 10 | 12 | 39:46 | -7 | 31 |
| 18 |
|
Recreativo Huelva | 29 | 7 | 9 | 13 | 27:41 | -14 | 30 |
| 19 |
|
CD Numancia | 29 | 8 | 3 | 18 | 33:59 | -26 | 27 |
| 20 |
|
Espanyol | 29 | 5 | 10 | 14 | 28:46 | -18 | 25 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
