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| 21.04.2009 | 21:00 | Real Madrid | - | Getafe CF | 3:2 (1:1) | |
| 21:00 | CD Numancia | - | Athletic Bilbao | 1:2 (1:1) | ||
| 22.04.2009 | 20:00 | CA Osasuna | - | Málaga CF | 2:3 (2:1) | |
| 20:00 | Deportivo La Coruña | - | UD Almería | 2:0 (0:0) | ||
| 20:00 | Real Betis | - | Valencia CF | 1:2 (0:0) | ||
| 22:00 | FC Barcelona | - | Sevilla FC | 4:0 (2:0) | ||
| 23.04.2009 | 20:00 | Villarreal CF | - | Recreativo Huelva | 2:1 (1:1) | |
| 20:00 | Sporting Gijón | - | Espanyol | 0:3 (0:1) | ||
| 22:00 | RCD Mallorca | - | Real Valladolid | 2:0 (0:0) | ||
| 22:00 | Racing Santander | - | Atlético Madrid | 5:1 (3:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 32 | 26 | 3 | 3 | 92:24 | 68 | 81 |
| 2 |
|
Real Madrid | 32 | 24 | 3 | 5 | 73:33 | 40 | 75 |
| 3 |
|
Sevilla FC | 32 | 17 | 6 | 9 | 44:34 | 10 | 57 |
| 4 |
|
Valencia CF | 32 | 16 | 7 | 9 | 60:45 | 15 | 55 |
| 5 |
|
Villarreal CF | 32 | 14 | 10 | 8 | 47:43 | 4 | 52 |
| 6 |
|
Málaga CF | 32 | 14 | 8 | 10 | 51:50 | 1 | 50 |
| 7 |
|
Atlético Madrid | 32 | 14 | 7 | 11 | 64:53 | 11 | 49 |
| 8 |
|
Deportivo La Coruña | 32 | 14 | 7 | 11 | 42:42 | 0 | 49 |
| 9 |
|
Real Valladolid | 32 | 12 | 4 | 16 | 42:51 | -9 | 40 |
| 10 |
|
Racing Santander | 32 | 10 | 9 | 13 | 43:40 | 3 | 39 |
| 11 |
|
RCD Mallorca | 32 | 10 | 9 | 13 | 39:49 | -10 | 39 |
| 12 |
|
Real Betis | 32 | 9 | 10 | 13 | 47:51 | -4 | 37 |
| 13 |
|
Athletic Bilbao | 32 | 10 | 7 | 15 | 42:53 | -11 | 37 |
| 14 |
|
UD Almería | 32 | 10 | 7 | 15 | 38:51 | -13 | 37 |
| 15 |
|
CA Osasuna | 32 | 8 | 11 | 13 | 37:41 | -4 | 35 |
| 16 |
|
Getafe CF | 32 | 8 | 10 | 14 | 42:50 | -8 | 34 |
| 17 |
|
Sporting Gijón | 32 | 11 | 0 | 21 | 38:69 | -31 | 33 |
| 18 |
|
Espanyol | 32 | 7 | 11 | 14 | 32:46 | -14 | 32 |
| 19 |
|
Recreativo Huelva | 32 | 7 | 9 | 16 | 28:46 | -18 | 30 |
| 20 |
|
CD Numancia | 32 | 8 | 4 | 20 | 34:64 | -30 | 28 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
