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| 20.02.2010 | 18:00 | Deportivo La Coruña | - | Xerez CD | 2:1 (2:1) | |
| 20:00 | FC Barcelona | - | Racing Santander | 4:0 (3:0) | ||
| 22:00 | RCD Mallorca | - | Sevilla FC | 1:3 (1:1) | ||
| 21.02.2010 | 17:00 | Málaga CF | - | Espanyol | 2:1 (1:1) | |
| 17:00 | Athletic Bilbao | - | CD Tenerife | 4:1 (2:0) | ||
| 17:00 | CA Osasuna | - | Real Valladolid | 1:1 (0:0) | ||
| 17:00 | Real Zaragoza | - | Sporting Gijón | 1:3 (0:1) | ||
| 19:00 | UD Almería | - | Atlético Madrid | 1:0 (0:0) | ||
| 21:00 | Real Madrid | - | Villarreal CF | 6:2 (2:1) | ||
| 22.02.2010 | 21:00 | Valencia CF | - | Getafe CF | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 23 | 18 | 4 | 1 | 57:13 | 44 | 58 |
| 2 |
|
Real Madrid | 23 | 18 | 2 | 3 | 59:17 | 42 | 56 |
| 3 |
|
Valencia CF | 23 | 13 | 7 | 3 | 41:22 | 19 | 46 |
| 4 |
|
Sevilla FC | 23 | 13 | 3 | 7 | 36:25 | 11 | 42 |
| 5 |
|
Deportivo La Coruña | 23 | 11 | 5 | 7 | 26:25 | 1 | 38 |
| 6 |
|
RCD Mallorca | 23 | 11 | 4 | 8 | 36:27 | 9 | 37 |
| 7 |
|
Athletic Bilbao | 23 | 11 | 3 | 9 | 32:30 | 2 | 36 |
| 8 |
|
Getafe CF | 23 | 10 | 2 | 11 | 31:30 | 1 | 32 |
| 9 |
|
CA Osasuna | 23 | 8 | 6 | 9 | 22:23 | -1 | 30 |
| 10 |
|
Villarreal CF | 23 | 8 | 5 | 10 | 35:37 | -2 | 29 |
| 11 |
|
Sporting Gijón | 23 | 7 | 7 | 9 | 25:27 | -2 | 28 |
| 12 |
|
Málaga CF | 23 | 6 | 9 | 8 | 28:27 | 1 | 27 |
| 13 |
|
Atlético Madrid | 23 | 7 | 6 | 10 | 33:36 | -3 | 27 |
| 14 |
|
UD Almería | 23 | 6 | 8 | 9 | 25:33 | -8 | 26 |
| 15 |
|
Espanyol | 23 | 7 | 5 | 11 | 17:31 | -14 | 26 |
| 16 |
|
Racing Santander | 23 | 6 | 7 | 10 | 24:35 | -11 | 25 |
| 17 |
|
Real Zaragoza | 23 | 5 | 6 | 12 | 27:47 | -20 | 21 |
| 18 |
|
CD Tenerife | 23 | 5 | 5 | 13 | 19:44 | -25 | 20 |
| 19 |
|
Real Valladolid | 23 | 3 | 11 | 9 | 26:40 | -14 | 20 |
| 20 |
|
Xerez CD | 23 | 2 | 5 | 16 | 13:43 | -30 | 11 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
