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| 23.10.2010 | 18:00 | Real Zaragoza | - | FC Barcelona | 0:2 (0:1) | |
| 20:00 | Real Madrid | - | Racing Santander | 6:1 (3:0) | ||
| 22:00 | Valencia CF | - | RCD Mallorca | 1:2 (1:2) | ||
| 24.10.2010 | 17:00 | Getafe CF | - | Sporting Gijón | 3:0 (1:0) | |
| 17:00 | UD Almería | - | Hércules CF | 1:1 (0:1) | ||
| 17:00 | CA Osasuna | - | Málaga CF | 3:0 (2:0) | ||
| 17:00 | Espanyol | - | Levante UD | 2:1 (1:0) | ||
| 19:00 | Sevilla FC | - | Athletic Bilbao | 4:3 (2:0) | ||
| 21:00 | Villarreal CF | - | Atlético Madrid | 2:0 (1:0) | ||
| 25.10.2010 | 21:00 | Real Sociedad | - | Deportivo La Coruña | 3:0 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Madrid | 8 | 6 | 2 | 0 | 22:4 | 18 | 20 |
| 2 |
|
Villarreal CF | 8 | 6 | 1 | 1 | 16:6 | 10 | 19 |
| 3 |
|
FC Barcelona | 8 | 6 | 1 | 1 | 14:6 | 8 | 19 |
| 4 |
|
Valencia CF | 8 | 5 | 1 | 2 | 13:8 | 5 | 16 |
| 5 |
|
Espanyol | 8 | 5 | 0 | 3 | 8:10 | -2 | 15 |
| 6 |
|
Sevilla FC | 8 | 4 | 2 | 2 | 14:11 | 3 | 14 |
| 7 |
|
Getafe CF | 8 | 4 | 1 | 3 | 14:10 | 4 | 13 |
| 8 |
|
Atlético Madrid | 8 | 4 | 1 | 3 | 12:9 | 3 | 13 |
| 9 |
|
RCD Mallorca | 8 | 3 | 2 | 3 | 7:8 | -1 | 11 |
| 10 |
|
Real Sociedad | 8 | 3 | 1 | 4 | 10:11 | -1 | 10 |
| 11 |
|
Athletic Bilbao | 8 | 3 | 1 | 4 | 14:14 | 0 | 10 |
| 12 |
|
CA Osasuna | 8 | 2 | 3 | 3 | 7:6 | 1 | 9 |
| 13 |
|
Hércules CF | 8 | 2 | 3 | 3 | 8:9 | -1 | 9 |
| 14 |
|
Sporting Gijón | 8 | 2 | 2 | 4 | 8:14 | -6 | 8 |
| 15 |
|
Levante UD | 8 | 2 | 2 | 4 | 8:14 | -6 | 8 |
| 16 |
|
UD Almería | 8 | 1 | 4 | 3 | 6:7 | -1 | 7 |
| 17 |
|
Málaga CF | 8 | 2 | 1 | 5 | 13:19 | -6 | 7 |
| 18 |
|
Racing Santander | 8 | 2 | 1 | 5 | 5:14 | -9 | 7 |
| 19 |
|
Deportivo La Coruña | 8 | 0 | 4 | 4 | 3:14 | -11 | 4 |
| 20 |
|
Real Zaragoza | 8 | 0 | 3 | 5 | 6:14 | -8 | 3 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Degradatie |
