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| 17.10.2021 | 14:30 | Campobasso | - | SSC Bari | 1:3 (1:1) | |
| 14:30 | Fidelis Andria | - | US Avellino | 1:1 (0:0) | ||
| 14:30 | Foggia Calcio | - | SS Monopoli 1966 | 1:0 (1:0) | ||
| 14:30 | SS Juve Stabia | - | AZ Picerno | 2:3 (1:2) | ||
| 14:30 | Monterosi FC | - | Paganese Calcio | 1:0 (1:0) | ||
| 14:30 | Potenza | - | ACR Messina | 2:3 (1:1) | ||
| 14:30 | FC Turris | - | Palermo FC | 3:0 (2:0) | ||
| 14:30 | US Catanzaro | - | Taranto FC | 3:0 (2:0) | ||
| 14:30 | Vibonese Calcio | - | Latina Calcio | 2:0 (1:0) | ||
| 14:30 | Virtus Francavilla | - | Calcio Catania | geannuleerd |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSC Bari | 8 | 6 | 2 | 0 | 17:5 | 12 | 20 |
| 2 |
|
US Catanzaro | 8 | 4 | 4 | 0 | 12:3 | 9 | 16 |
| 3 |
|
Foggia Calcio | 9 | 4 | 3 | 2 | 13:9 | 4 | 15 |
| 4 |
|
FC Turris | 8 | 4 | 1 | 3 | 15:9 | 6 | 13 |
| 5 |
|
Palermo FC | 9 | 3 | 4 | 2 | 11:9 | 2 | 13 |
| 6 |
|
Taranto FC | 9 | 3 | 4 | 2 | 7:6 | 1 | 13 |
|
Virtus Francavilla | 8 | 4 | 1 | 3 | 7:6 | 1 | 13 | |
| 8 |
|
Monterosi FC | 9 | 3 | 4 | 2 | 10:11 | -1 | 13 |
| 9 |
|
US Avellino | 9 | 2 | 6 | 1 | 6:5 | 1 | 12 |
| 10 |
|
Campobasso | 9 | 3 | 2 | 4 | 11:14 | -3 | 11 |
| 11 |
|
AZ Picerno | 8 | 3 | 2 | 3 | 6:9 | -3 | 11 |
| 12 |
|
SS Monopoli 1966 | 8 | 3 | 1 | 4 | 8:9 | -1 | 10 |
| 13 |
|
SS Juve Stabia | 8 | 2 | 5 | 1 | 8:6 | 2 | 9 |
| 14 |
|
Latina Calcio | 9 | 2 | 2 | 5 | 8:12 | -4 | 8 |
| 15 |
|
Paganese Calcio | 8 | 2 | 2 | 4 | 8:13 | -5 | 8 |
| 16 |
|
ACR Messina | 9 | 2 | 2 | 5 | 13:19 | -6 | 8 |
| 17 |
|
Potenza | 9 | 1 | 4 | 4 | 9:13 | -4 | 7 |
| 18 |
|
Vibonese Calcio | 9 | 1 | 4 | 4 | 6:11 | -5 | 7 |
| 19 |
|
Fidelis Andria | 8 | 1 | 3 | 4 | 7:13 | -6 | 6 |
| 20 |
|
Calcio Catania | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
