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| 30.03.2022 | 15:00 | Cascina | - | San Donato Tavarnelle | 1:0 | |
| 15:00 | Foligno Calcio | - | US Poggibonsi | 0:2 | ||
| 15:00 | Follonica Gavorrano | - | US Pianese | 1:2 | ||
| 15:00 | Montespaccato | - | Scandicci Calcio | 1:1 | ||
| 15:00 | FC Rieti | - | ASD Cannara | 2:1 | ||
| 15:00 | AC Sangiovannese | - | Pro Livorno Sorgenti | 1:1 | ||
| 15:00 | SC Trestina | - | Virtus Flaminia | 1:1 | ||
| 15:00 | Unipomezia Virtus | - | Badesse Calcio | 1:1 | ||
| 18:30 | US Arezzo | - | SSD Tiferno Lerchi | 2:1 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
San Donato Tavarnelle | 26 | 19 | 3 | 4 | 69:24 | 45 | 60 |
| 2 |
|
US Poggibonsi | 26 | 18 | 4 | 4 | 42:19 | 23 | 58 |
| 3 |
|
Follonica Gavorrano | 26 | 13 | 9 | 4 | 44:21 | 23 | 48 |
| 4 |
|
US Arezzo | 26 | 13 | 9 | 4 | 47:33 | 14 | 48 |
| 5 |
|
Badesse Calcio | 26 | 12 | 7 | 7 | 37:33 | 4 | 43 |
| 6 |
|
SC Trestina | 26 | 11 | 9 | 6 | 38:25 | 13 | 42 |
| 7 |
|
US Pianese | 26 | 11 | 7 | 8 | 41:35 | 6 | 40 |
| 8 |
|
SSD Tiferno Lerchi | 26 | 10 | 9 | 7 | 32:33 | -1 | 39 |
| 9 |
|
Virtus Flaminia | 26 | 9 | 7 | 10 | 39:41 | -2 | 34 |
| 10 |
|
Montespaccato | 26 | 9 | 7 | 10 | 34:31 | 3 | 34 |
| 11 |
|
Scandicci Calcio | 26 | 9 | 6 | 11 | 27:34 | -7 | 33 |
| 12 |
|
AC Sangiovannese | 26 | 6 | 10 | 10 | 30:35 | -5 | 28 |
| 13 |
|
Unipomezia Virtus | 26 | 7 | 6 | 13 | 32:49 | -17 | 27 |
| 14 |
|
Foligno Calcio | 26 | 7 | 6 | 13 | 35:52 | -17 | 27 |
| 15 |
|
Cascina | 26 | 6 | 6 | 14 | 24:34 | -10 | 24 |
| 16 |
|
FC Rieti | 26 | 6 | 6 | 14 | 28:46 | -18 | 24 |
| 17 |
|
ASD Cannara | 26 | 4 | 6 | 16 | 19:36 | -17 | 18 |
| 18 |
|
Pro Livorno Sorgenti | 26 | 3 | 5 | 18 | 24:61 | -37 | 14 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
