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| 27.04.2022 | 15:00 | ASD Cannara | - | Foligno Calcio | 0:3 | |
| 15:00 | Virtus Flaminia | - | Follonica Gavorrano | 3:1 | ||
| 15:00 | Badesse Calcio | - | Montespaccato | 2:1 | ||
| 15:00 | US Pianese | - | US Arezzo | 2:2 | ||
| 15:00 | Pro Livorno Sorgenti | - | SSD Tiferno Lerchi | 1:0 | ||
| 15:00 | Scandicci Calcio | - | AC Sangiovannese | 0:0 | ||
| 15:00 | SC Trestina | - | Cascina | 0:1 | ||
| 15:00 | Unipomezia Virtus | - | FC Rieti | 4:1 | ||
| 15:00 | US Poggibonsi | - | San Donato Tavarnelle | 1:2 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
San Donato Tavarnelle | 31 | 23 | 3 | 5 | 83:30 | 53 | 72 |
| 2 |
|
US Poggibonsi | 31 | 21 | 4 | 6 | 51:25 | 26 | 67 |
| 3 |
|
US Arezzo | 31 | 16 | 10 | 5 | 60:41 | 19 | 58 |
| 4 |
|
Follonica Gavorrano | 31 | 15 | 9 | 7 | 52:28 | 24 | 54 |
| 5 |
|
US Pianese | 31 | 14 | 8 | 9 | 50:38 | 12 | 50 |
| 6 |
|
Badesse Calcio | 31 | 14 | 8 | 9 | 42:38 | 4 | 50 |
| 7 |
|
SC Trestina | 31 | 12 | 10 | 9 | 44:33 | 11 | 46 |
| 8 |
|
Virtus Flaminia | 31 | 13 | 7 | 11 | 47:44 | 3 | 46 |
| 9 |
|
SSD Tiferno Lerchi | 31 | 10 | 10 | 11 | 33:42 | -9 | 40 |
| 10 |
|
Scandicci Calcio | 31 | 10 | 9 | 12 | 32:39 | -7 | 39 |
| 11 |
|
Montespaccato | 31 | 10 | 7 | 14 | 37:40 | -3 | 37 |
| 12 |
|
Cascina | 31 | 10 | 7 | 14 | 33:35 | -2 | 37 |
| 13 |
|
AC Sangiovannese | 31 | 7 | 13 | 11 | 33:38 | -5 | 34 |
| 14 |
|
FC Rieti | 31 | 9 | 7 | 15 | 36:53 | -17 | 34 |
| 15 |
|
Foligno Calcio | 31 | 8 | 7 | 16 | 41:59 | -18 | 31 |
| 16 |
|
Unipomezia Virtus | 31 | 8 | 6 | 17 | 37:60 | -23 | 30 |
| 17 |
|
ASD Cannara | 31 | 5 | 8 | 18 | 25:48 | -23 | 23 |
| 18 |
|
Pro Livorno Sorgenti | 31 | 5 | 5 | 21 | 29:74 | -45 | 20 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
