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| 30.05.2021 | 16:00 | Audace Cerignola | - | Città di Fasano | 4:0 | |
| 16:00 | US Bitonto | - | FBC Gravina | 0:1 | ||
| 16:00 | FC Francavilla | - | Taranto FC | 0:0 | ||
| 16:00 | Lavello | - | ACD Nardò | 2:0 | ||
| 16:00 | Sporting Fulgor Molfetta | - | Fidelis Andria | 0:2 | ||
| 16:00 | AZ Picerno | - | Aversa Normanna | 3:1 | ||
| 16:00 | Portici 1906 | - | Team Altamura | 3:0 | ||
| 16:00 | Puteolana Internapoli | - | Brindisi | 0:0 | ||
| 16:00 | Sorrento Calcio | - | Casarano | 2:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Taranto FC | 32 | 17 | 12 | 3 | 43:19 | 24 | 63 |
| 2 |
|
AZ Picerno | 32 | 17 | 11 | 4 | 53:33 | 20 | 62 |
| 3 |
|
Fidelis Andria | 32 | 15 | 12 | 5 | 38:18 | 20 | 57 |
| 4 |
|
Lavello | 32 | 14 | 12 | 6 | 53:35 | 18 | 54 |
| 5 |
|
US Bitonto | 32 | 15 | 6 | 11 | 45:37 | 8 | 51 |
| 6 |
|
Audace Cerignola | 32 | 13 | 10 | 9 | 56:34 | 22 | 49 |
| 7 |
|
Casarano | 32 | 13 | 10 | 9 | 47:39 | 8 | 49 |
| 8 |
|
ACD Nardò | 32 | 13 | 9 | 10 | 43:34 | 9 | 48 |
| 9 |
|
Team Altamura | 32 | 11 | 10 | 11 | 44:40 | 4 | 43 |
| 10 |
|
Sporting Fulgor Molfetta | 32 | 11 | 8 | 13 | 50:54 | -4 | 41 |
| 11 |
|
Sorrento Calcio | 32 | 10 | 10 | 12 | 36:48 | -12 | 40 |
| 12 |
|
Città di Fasano | 32 | 8 | 11 | 13 | 34:44 | -10 | 35 |
| 13 |
|
FC Francavilla | 32 | 7 | 12 | 13 | 34:45 | -11 | 33 |
| 14 |
|
FBC Gravina | 32 | 7 | 11 | 14 | 29:34 | -5 | 32 |
| 15 |
|
Portici 1906 | 32 | 9 | 4 | 19 | 45:69 | -24 | 31 |
| 16 |
|
Aversa Normanna | 32 | 8 | 6 | 18 | 35:53 | -18 | 30 |
| 17 |
|
Brindisi | 32 | 7 | 11 | 14 | 25:43 | -18 | 30 |
| 18 |
|
Puteolana Internapoli | 32 | 5 | 11 | 16 | 22:53 | -31 | 26 |
| Promotie | |
| Play-offs | |
| Degradatie |
