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| 13.06.2021 | 16:00 | Acireale | - | Dattilo | 1:1 | |
| 16:00 | Biancavilla | - | Santa Maria Cilento | 1:1 | ||
| 16:00 | Calcio Cittanovese | - | ASD San Luca | 1:2 | ||
| 16:00 | FC Messina | - | US Castrovillari | 2:1 | ||
| 16:00 | Gelbison | - | Roccella | 4:0 | ||
| 16:00 | Licata | - | ACR Messina | 1:1 | ||
| 16:00 | USD Ragusa | - | ASD Troina | 1:0 | ||
| 16:00 | Rotonda | - | Paternó | 1:0 | ||
| 16:00 | Città Di S. Agata | - | Rende | 2:1 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
ACR Messina | 32 | 19 | 11 | 2 | 60:24 | 36 | 68 |
| 2 |
|
FC Messina | 32 | 19 | 9 | 4 | 49:22 | 27 | 66 |
| 3 |
|
Gelbison | 32 | 17 | 9 | 6 | 51:33 | 18 | 60 |
| 4 |
|
ASD San Luca | 32 | 16 | 7 | 9 | 43:35 | 8 | 55 |
| 5 |
|
Acireale | 32 | 16 | 6 | 10 | 48:30 | 18 | 54 |
| 6 |
|
Dattilo | 32 | 16 | 4 | 12 | 52:45 | 7 | 52 |
| 7 |
|
Rotonda | 32 | 12 | 10 | 10 | 30:31 | -1 | 46 |
| 8 |
|
Santa Maria Cilento | 32 | 9 | 15 | 8 | 41:27 | 14 | 42 |
| 9 |
|
Biancavilla | 32 | 13 | 4 | 15 | 38:42 | -4 | 42 |
| 10 |
|
US Castrovillari | 32 | 10 | 10 | 12 | 37:34 | 3 | 40 |
| 11 |
|
Licata | 32 | 10 | 10 | 12 | 32:33 | -1 | 40 |
| 12 |
|
Paternó | 32 | 10 | 9 | 13 | 26:30 | -4 | 39 |
| 13 |
|
ASD Troina | 32 | 9 | 9 | 14 | 25:41 | -16 | 36 |
| 14 |
|
Calcio Cittanovese | 32 | 8 | 9 | 15 | 36:48 | -12 | 33 |
| 15 |
|
Città Di S. Agata | 32 | 7 | 12 | 13 | 26:43 | -17 | 33 |
| 16 |
|
Rende | 32 | 8 | 7 | 17 | 32:52 | -20 | 31 |
| 17 |
|
USD Ragusa | 32 | 7 | 9 | 16 | 35:54 | -19 | 30 |
| 18 |
|
Roccella | 32 | 5 | 4 | 23 | 23:60 | -37 | 19 |
| Promotie | |
| Play-offs | |
| Degradatie |
