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| 06.10.2021 | 14:30 | Sancataldese Calcio | - | Cavese | 0:2 (0:1) | |
| 15:00 | Biancavilla | - | Gelbison | 0:1 (0:0) | ||
| 15:00 | US Castrovillari | - | Portici 1906 | 1:2 (1:1) | ||
| 15:00 | FC Messina | - | Calcio Cittanovese | geannuleerd | ||
| 15:00 | Giarre | - | Lamezia Terme | 0:1 (0:1) | ||
| 15:00 | Licata | - | ASD San Luca | 2:0 (1:0) | ||
| 15:00 | Rende | - | Città Di S. Agata | 0:1 (0:0) | ||
| 15:00 | Santa Maria Cilento | - | Paternó | 1:1 (0:1) | ||
| 15:00 | ASD Troina | - | Aversa Normanna | 4:5 (2:4) | ||
| 17.11.2021 | 14:30 | Trapani Calcio | - | Acireale | 0:0 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cavese | 4 | 4 | 0 | 0 | 6:0 | 6 | 12 |
| 2 |
|
Portici 1906 | 4 | 4 | 0 | 0 | 9:4 | 5 | 12 |
| 3 |
|
Gelbison | 4 | 3 | 1 | 0 | 5:1 | 4 | 10 |
| 4 |
|
Paternó | 4 | 3 | 1 | 0 | 7:4 | 3 | 10 |
| 5 |
|
Città Di S. Agata | 4 | 3 | 0 | 1 | 5:2 | 3 | 9 |
| 6 |
|
Aversa Normanna | 4 | 3 | 0 | 1 | 7:7 | 0 | 9 |
| 7 |
|
Lamezia Terme | 4 | 2 | 1 | 1 | 4:3 | 1 | 7 |
| 8 |
|
ASD San Luca | 3 | 2 | 0 | 1 | 5:4 | 1 | 6 |
| 9 |
|
Santa Maria Cilento | 4 | 1 | 2 | 1 | 4:2 | 2 | 5 |
| 10 |
|
Acireale | 3 | 1 | 2 | 0 | 1:0 | 1 | 5 |
| 11 |
|
Licata | 3 | 1 | 1 | 1 | 5:4 | 1 | 4 |
| 12 |
|
Trapani Calcio | 4 | 1 | 1 | 2 | 2:3 | -1 | 4 |
| 13 |
|
Calcio Cittanovese | 3 | 1 | 0 | 2 | 1:2 | -1 | 3 |
| 14 |
|
US Castrovillari | 4 | 1 | 0 | 3 | 5:8 | -3 | 3 |
| 15 |
|
Biancavilla | 4 | 1 | 0 | 3 | 4:7 | -3 | 2 |
| 16 |
|
Rende | 4 | 0 | 1 | 3 | 3:7 | -4 | 1 |
| 17 |
|
FC Messina | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| 18 |
|
Giarre | 4 | 0 | 0 | 4 | 2:6 | -4 | 0 |
| 19 |
|
Sancataldese Calcio | 4 | 0 | 0 | 4 | 0:6 | -6 | 0 |
| 20 |
|
ASD Troina | 4 | 0 | 0 | 4 | 5:10 | -5 | -6 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
