| 2. Ronde | 14.08.2021 | Rochdale AFC | - | Scunthorpe United | 0:0 | ||||
| 3. Ronde | 17.08.2021 | Walsall FC | - | Scunthorpe United | 1:1 | ||||
| 4. Ronde | 21.08.2021 | Scunthorpe United | - | Sutton United | 1:1 |  |
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| 6. Ronde | 04.09.2021 | Northampton Town | - | Scunthorpe United | 2:0 | ||||
| 7. Ronde | 11.09.2021 | Scunthorpe United | - | Exeter City | 0:4 | ||||
| 8. Ronde | 18.09.2021 | Carlisle United | - | Scunthorpe United | 2:2 | |
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| 9. Ronde | 25.09.2021 | Scunthorpe United | - | Port Vale FC | 0:1 | ||||
| 10. Ronde | 02.10.2021 | Newport County | - | Scunthorpe United | 3:0 | ||||
| 16. Ronde | 13.11.2021 | Scunthorpe United | - | Salford City | 1:1 | |
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| 17. Ronde | 20.11.2021 | Mansfield Town | - | Scunthorpe United | 3:1 | ||||
| 18. Ronde | 23.11.2021 | Scunthorpe United | - | Leyton Orient | 1:1 | |
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| 19. Ronde | 27.11.2021 | Scunthorpe United | - | Bradford City | 1:1 | ||||
| 28. Ronde | 22.01.2022 | Scunthorpe United | - | Newport County | 0:1 | ||||
| 22. Ronde | 25.01.2022 | Scunthorpe United | - | Bristol Rovers | 2:3 |
Engeland