| 17. Ronde | 16.01.2022 | Middlesbrough FC U23 | - | Sunderland AFC U23 | 3:2 |  |
|||
| 18. Ronde | 23.01.2022 | Southampton FC U23 | - | Middlesbrough FC U23 | 1:0 | ||||
| 19. Ronde | 04.02.2022 | Norwich City U23 | - | Middlesbrough FC U23 | 4:0 | ||||
| 21. Ronde | 27.02.2022 | Birmingham City U23 | - | Middlesbrough FC U23 | 4:2 | |
|||
| 22. Ronde | 14.03.2022 | Stoke City U23 | - | Middlesbrough FC U23 | 1:0 | ||||
| 23. Ronde | 18.03.2022 | Middlesbrough FC U23 | - | Fulham FC U23 | 0:0 | ||||
| 24. Ronde | 01.04.2022 | Middlesbrough FC U23 | - | Newcastle United U23 | 4:2 |  |
|||
| 20. Ronde | 15.04.2022 | Middlesbrough FC U23 | - | Wolverhampton Wanderers U23 | 0:3 | ||||
| 25. Ronde | 22.04.2022 | Nottingham Forest U23 | - | Middlesbrough FC U23 | 1:1 | |
|||
| 26. Ronde | 01.05.2022 | Middlesbrough FC U23 | - | Reading FC U23 | 2:1 |
Engeland