| 7. Ronde | 20.02.2021 | Boca Juniors de Cali | - | Orsomarso SC | 0:0 | ||||
| 8. Ronde | 27.02.2021 | Orsomarso SC | - | Real Cartagena | 3:3 | ||||
| 9. Ronde | 04.03.2021 | Real Santander | - | Orsomarso SC | 1:2 |  |
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| 10. Ronde | 07.03.2021 | Orsomarso SC | - | Bogotá FC | 4:2 | ||||
| 11. Ronde | 14.03.2021 | Fortaleza FC | - | Orsomarso SC | 3:1 | ||||
| 12. Ronde | 22.03.2021 | Orsomarso SC | - | Leones FC | 1:1 | ||||
| 13. Ronde | 27.03.2021 | Atlético Huila | - | Orsomarso SC | 3:2 | |
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| 14. Ronde | 03.04.2021 | Orsomarso SC | - | Cortuluá | 1:2 | ||||
| 15. Ronde | 09.04.2021 | Atlético FC | - | Orsomarso SC | 0:0 | |
Colombia