| 1. Ronde | 14.08.2021 | Norwich City [U18] | - | Southampton FC [U18] | 0:2 | ||||
| 2. Ronde | 21.08.2021 | Southampton FC [U18] | - | Birmingham City [U18] | 7:2 | ||||
| 3. Ronde | 28.08.2021 | West Ham United [U18] | - | Southampton FC [U18] | 1:3 | ||||
| 4. Ronde | 11.09.2021 | Southampton FC [U18] | - | Arsenal FC [U18] | 3:3 |  |
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| 7. Ronde | 23.10.2021 | West Bromwich Albion [U18] | - | Southampton FC [U18] | 1:5 | ||||
| 8. Ronde | 30.10.2021 | Southampton FC [U18] | - | Brighton & Hove Albion [U18] | 3:2 | ||||
| 9. Ronde | 06.11.2021 | Southampton FC [U18] | - | Aston Villa [U18] | 6:3 | ||||
| 10. Ronde | 20.11.2021 | Tottenham Hotspur [U18] | - | Southampton FC [U18] | 0:3 | ||||
| 11. Ronde | 04.12.2021 | Southampton FC [U18] | - | Fulham FC [U18] | 2:0 | ||||
| 14. Ronde | 15.01.2022 | Southampton FC [U18] | - | Tottenham Hotspur [U18] | 1:2 | ||||
| 26. Ronde | 07.05.2022 | Southampton FC [U18] | - | Chelsea FC [U18] | 5:2 |
Engeland