| 1. Ronde | 16.08.2021 | Newcastle United U23 | - | Reading FC U23 | 1:1 |  |
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| 2. Ronde | 23.08.2021 | Reading FC U23 | - | Wolverhampton Wanderers U23 | 3:0 | |
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| 3. Ronde | 29.08.2021 | Stoke City U23 | - | Reading FC U23 | 1:2 |  |
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| 4. Ronde | 12.09.2021 | Reading FC U23 | - | Nottingham Forest U23 | 0:2 | ||||
| 5. Ronde | 20.09.2021 | Reading FC U23 | - | Norwich City U23 | 3:3 | |
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| 6. Ronde | 27.09.2021 | Burnley FC U23 | - | Reading FC U23 | 3:1 | ||||
| 7. Ronde | 04.10.2021 | Reading FC U23 | - | Birmingham City U23 | 1:1 | ||||
| 9. Ronde | 25.10.2021 | Reading FC U23 | - | Southampton FC U23 | 0:1 | ||||
| 10. Ronde | 01.11.2021 | Reading FC U23 | - | Sunderland AFC U23 | 0:3 | |
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| 12. Ronde | 22.11.2021 | West Bromwich Albion U23 | - | Reading FC U23 | 1:1 | |
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| 14. Ronde | 03.12.2021 | Norwich City U23 | - | Reading FC U23 | 5:2 | |
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| 16. Ronde | 10.01.2022 | Sunderland AFC U23 | - | Reading FC U23 | 2:0 | ||||
| 19. Ronde | 07.02.2022 | Reading FC U23 | - | Stoke City U23 | 1:1 | ||||
| 20. Ronde | 21.02.2022 | Nottingham Forest U23 | - | Reading FC U23 | 7:0 | ||||
| 15. Ronde | 06.03.2022 | Birmingham City U23 | - | Reading FC U23 | 0:0 | |
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| 23. Ronde | 20.03.2022 | Southampton FC U23 | - | Reading FC U23 | 2:1 |
Engeland