| 5. Ronde | 19.09.2021 | Southampton FC U23 | - | Burnley FC U23 | 0:2 | ||||
| 17. Ronde | 17.01.2022 | Southampton FC U23 | - | Fulham FC U23 | 2:1 | ||||
| 18. Ronde | 23.01.2022 | Southampton FC U23 | - | Middlesbrough FC U23 | 1:0 | ||||
| 20. Ronde | 21.02.2022 | Southampton FC U23 | - | Birmingham City U23 | 2:3 | ||||
| 21. Ronde | 26.02.2022 | Southampton FC U23 | - | Nottingham Forest U23 | 4:2 | ||||
| 22. Ronde | 11.03.2022 | Aston Villa U23 | - | Southampton FC U23 | 2:2 |
Engeland