| 26. Ronde | 20.02.2022 | Wolverhampton Wanderers | - | Leicester City | 2:1 | ||||
| 20. Ronde | 24.02.2022 | Arsenal FC | - | Wolverhampton Wanderers | 2:1 | ||||
| 27. Ronde | 27.02.2022 | West Ham United | - | Wolverhampton Wanderers | 1:0 | ||||
| 28. Ronde | 05.03.2022 | Wolverhampton Wanderers | - | Crystal Palace | 0:2 | ||||
| 19. Ronde | 10.03.2022 | Wolverhampton Wanderers | - | Watford FC | 4:0 | ||||
| 31. Ronde | 02.04.2022 | Wolverhampton Wanderers | - | Aston Villa | 2:1 |  |
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| 32. Ronde | 08.04.2022 | Newcastle United | - | Wolverhampton Wanderers | 1:0 | ||||
| 34. Ronde | 24.04.2022 | Burnley FC | - | Wolverhampton Wanderers | 1:0 | |
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| 35. Ronde | 30.04.2022 | Wolverhampton Wanderers | - | Brighton & Hove Albion | 0:3 | ||||
| 36. Ronde | 07.05.2022 | Chelsea FC | - | Wolverhampton Wanderers | 2:2 | |
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| 33. Ronde | 11.05.2022 | Wolverhampton Wanderers | - | Manchester City | 1:5 | ||||
| 37. Ronde | 15.05.2022 | Wolverhampton Wanderers | - | Norwich City | 1:1 | ||||
| 38. Ronde | 22.05.2022 | Liverpool FC | - | Wolverhampton Wanderers | 3:1 |  |
Portugal