| 1. Ronde | 16.08.2021 | Wolverhampton Wanderers U23 | - | Middlesbrough FC U23 | 2:1 | ||||
| 6. Ronde | 24.09.2021 | Middlesbrough FC U23 | - | Nottingham Forest U23 | 0:1 | ||||
| 7. Ronde | 01.10.2021 | Newcastle United U23 | - | Middlesbrough FC U23 | 4:1 | ||||
| 8. Ronde | 17.10.2021 | Middlesbrough FC U23 | - | West Bromwich Albion U23 | 1:2 | ||||
| 9. Ronde | 22.10.2021 | Burnley FC U23 | - | Middlesbrough FC U23 | 2:0 | ||||
| 16. Ronde | 10.01.2022 | Aston Villa U23 | - | Middlesbrough FC U23 | 1:2 | ||||
| 18. Ronde | 23.01.2022 | Southampton FC U23 | - | Middlesbrough FC U23 | 1:0 | ||||
| 19. Ronde | 04.02.2022 | Norwich City U23 | - | Middlesbrough FC U23 | 4:0 | ||||
| 22. Ronde | 14.03.2022 | Stoke City U23 | - | Middlesbrough FC U23 | 1:0 | ||||
| 23. Ronde | 18.03.2022 | Middlesbrough FC U23 | - | Fulham FC U23 | 0:0 | ||||
| 24. Ronde | 01.04.2022 | Middlesbrough FC U23 | - | Newcastle United U23 | 4:2 | ||||
| 20. Ronde | 15.04.2022 | Middlesbrough FC U23 | - | Wolverhampton Wanderers U23 | 0:3 | ||||
| 26. Ronde | 01.05.2022 | Middlesbrough FC U23 | - | Reading FC U23 | 2:1 |
Engeland