| 4. Ronde | 11.09.2021 | Tottenham Hotspur [U18] | - | Reading FC [U18] | 3:2 | ||||
| 10. Ronde | 20.11.2021 | Birmingham City [U18] | - | Reading FC [U18] | 1:3 | ||||
| 11. Ronde | 04.12.2021 | Reading FC [U18] | - | Norwich City [U18] | 2:0 | ||||
| 15. Ronde | 22.01.2022 | Norwich City [U18] | - | Reading FC [U18] | 1:4 | ||||
| 19. Ronde | 05.03.2022 | Reading FC [U18] | - | West Ham United [U18] | 0:6 | ||||
| 20. Ronde | 12.03.2022 | Fulham FC [U18] | - | Reading FC [U18] | 5:0 | ||||
| 17. Ronde | 16.03.2022 | Reading FC [U18] | - | Chelsea FC [U18] | 2:2 | ||||
| 21. Ronde | 19.03.2022 | Reading FC [U18] | - | Leicester City [U18] | 1:1 |  |
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| 14. Ronde | 22.03.2022 | Reading FC [U18] | - | Birmingham City [U18] | 3:1 | ||||
| 22. Ronde | 02.04.2022 | Reading FC [U18] | - | Tottenham Hotspur [U18] | 1:2 | ||||
| 24. Ronde | 23.04.2022 | Crystal Palace [U18] | - | Reading FC [U18] | 3:0 |
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