| 25. Ronde | 06.02.2022 | Delfino Pescara | - | AS Gubbio | 3:1 | ||||
| 28. Ronde | 20.02.2022 | AS Gubbio | - | SSD Città di Teramo | 2:2 | ||||
| 29. Ronde | 27.02.2022 | Carrarese Calcio | - | AS Gubbio | 1:0 | ||||
| 32. Ronde | 15.03.2022 | AS Gubbio | - | Imolese Calcio | 2:1 | ||||
| 33. Ronde | 19.03.2022 | Lucchese | - | AS Gubbio | 2:2 | ||||
| 34. Ronde | 27.03.2022 | AS Gubbio | - | Viterbese | 1:2 | ||||
| 35. Ronde | 03.04.2022 | Ancona 1905 | - | AS Gubbio | 0:2 | ||||
| 36. Ronde | 09.04.2022 | AS Gubbio | - | US Pistoiese | 2:2 | ||||
| 37. Ronde | 14.04.2022 | AS Gubbio | - | Modena FC | 1:1 | ||||
| 38. Ronde | 23.04.2022 | Aquila Montevarchi | - | AS Gubbio | 2:1 |
Italië